ZNF263 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006355Biological processregulation of DNA-templated transcription
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding
GO_0046872Molecular functionmetal ion binding
GO_0000976Molecular functiontranscription cis-regulatory region binding

IV. Literature review

[source]
Gene nameZNF263
Protein nameZinc finger protein 263
Zinc finger protein 263 (Zinc finger protein FPM315) (Zinc finger protein with KRAB and SCAN domains 12)
SynonymsZKSCAN12
FPM315
hCG_2039169
DescriptionFUNCTION: Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor . Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression . Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions . .

AccessionsO14978
ENST00000574253.2
ENST00000572748.2
D3DUC1
ENST00000574674.2
I3L0N0
ENST00000219069.6
I3L393
I3L2X3
ENST00000573578.1
ENST00000575823.2
I3NI39
ENST00000575332.2