ZNF16 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZNF16 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZNF16 at tissue level.

III. Associated gene sets

GO_0008284Biological processpositive regulation of cell population proliferation
GO_0033674Biological processpositive regulation of kinase activity
GO_0051781Biological processpositive regulation of cell division
GO_0045654Biological processpositive regulation of megakaryocyte differentiation
GO_0051301Biological processcell division
GO_0043066Biological processnegative regulation of apoptotic process
GO_0045648Biological processpositive regulation of erythrocyte differentiation
GO_0072707Biological processcellular response to sodium dodecyl sulfate
GO_1901989Biological processpositive regulation of cell cycle phase transition
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZNF16
Protein nameZinc finger protein 16 (Zinc finger protein KOX9)
Alternative protein ZNF16
Zinc finger protein 16
SynonymsHZF1
KOX9
DescriptionFUNCTION: Acts as a transcriptional activator. Promotes cell proliferation by facilitating the cell cycle phase transition from the S to G2/M phase. Involved in both the hemin- and phorbol myristate acetate (PMA)-induced erythroid and megakaryocytic differentiation, respectively. Also plays a role as an inhibitor of cell apoptosis. .

AccessionsENST00000611477.1
E9PQV1
L8EAK2
P17020
ENST00000527811.5
E9PNT9
ENST00000532351.5
ENST00000276816.8
ENST00000394909.7