ZFYVE28 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007175Biological processnegative regulation of epidermal growth factor-activated receptor activity
GO_0042059Biological processnegative regulation of epidermal growth factor receptor signaling pathway
GO_0031901Cellular componentearly endosome membrane
GO_0005829Cellular componentcytosol
GO_0032266Molecular functionphosphatidylinositol-3-phosphate binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZFYVE28
Protein nameZinc finger FYVE-type containing 28
Lateral signaling target protein 2 homolog (hLst2) (Zinc finger FYVE domain-containing protein 28)
ZFYVE28 protein (Zinc finger FYVE-type containing 28)
SynonymsLST2
KIAA1643
DescriptionFUNCTION: Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated. .

AccessionsENST00000515169.5 [Q9HCC9-8]
Q9HCC9
D6RID3
ENST00000508184.5
ENST00000509171.5 [Q9HCC9-7]
ENST00000503000.1 [Q9HCC9-6]
ENST00000511071.5 [Q9HCC9-2]
ENST00000515312.5 [Q9HCC9-3]
ENST00000508471.5
Q49AA1
ENST00000290974.7 [Q9HCC9-1]