Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 11 studies | 24% ± 8% | |
epithelial cell | 7 studies | 28% ± 14% | |
ciliated cell | 6 studies | 27% ± 9% | |
type I pneumocyte | 6 studies | 20% ± 5% | |
endothelial cell | 4 studies | 23% ± 6% | |
type II pneumocyte | 4 studies | 19% ± 4% | |
basal cell | 4 studies | 28% ± 8% | |
glutamatergic neuron | 4 studies | 29% ± 6% | |
oligodendrocyte precursor cell | 4 studies | 25% ± 6% | |
myofibroblast cell | 3 studies | 21% ± 2% | |
GABAergic neuron | 3 studies | 30% ± 2% | |
abnormal cell | 3 studies | 23% ± 5% | |
neuron | 3 studies | 28% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 20202.53 | 245 / 245 | 100% | 135.97 | 500 / 502 |
thymus | 100% | 27105.75 | 653 / 653 | 99% | 126.76 | 600 / 605 |
breast | 100% | 9841.02 | 459 / 459 | 99% | 89.36 | 1102 / 1118 |
pancreas | 100% | 10447.97 | 328 / 328 | 98% | 71.14 | 175 / 178 |
intestine | 100% | 14682.73 | 966 / 966 | 98% | 68.80 | 518 / 527 |
ovary | 100% | 27808.76 | 180 / 180 | 98% | 73.59 | 421 / 430 |
bladder | 100% | 15234.48 | 21 / 21 | 98% | 80.38 | 493 / 504 |
esophagus | 100% | 10795.38 | 1443 / 1445 | 98% | 51.65 | 179 / 183 |
lung | 100% | 10258.95 | 578 / 578 | 97% | 61.63 | 1126 / 1155 |
uterus | 100% | 19689.37 | 170 / 170 | 97% | 77.01 | 447 / 459 |
skin | 99% | 6251.67 | 1793 / 1809 | 98% | 72.34 | 462 / 472 |
stomach | 100% | 9870.82 | 359 / 359 | 97% | 58.64 | 276 / 286 |
kidney | 100% | 11783.25 | 89 / 89 | 96% | 62.97 | 868 / 901 |
adrenal gland | 100% | 17077.55 | 258 / 258 | 95% | 72.07 | 219 / 230 |
brain | 95% | 6480.18 | 2520 / 2642 | 100% | 138.86 | 703 / 705 |
liver | 100% | 5715.75 | 225 / 226 | 84% | 34.61 | 341 / 406 |
spleen | 100% | 14029.07 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 38.63 | 1 / 1 |
blood vessel | 100% | 9679.10 | 1333 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 7375.41 | 1199 / 1204 | 0% | 0 | 0 / 0 |
muscle | 98% | 5458.77 | 790 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 66.05 | 44 / 45 |
heart | 94% | 5810.69 | 813 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 51.26 | 75 / 80 |
lymph node | 0% | 0 | 0 / 0 | 93% | 66.03 | 27 / 29 |
peripheral blood | 76% | 4803.85 | 709 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010507 | Biological process | negative regulation of autophagy |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0070314 | Biological process | G1 to G0 transition |
GO_0002130 | Biological process | wobble position ribose methylation |
GO_0030488 | Biological process | tRNA methylation |
GO_0008180 | Cellular component | COP9 signalosome |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0000049 | Molecular function | tRNA binding |
GO_0030234 | Molecular function | enzyme regulator activity |
GO_0005515 | Molecular function | protein binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | WDR6 |
Protein name | tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6) WD repeat domain 6 |
Synonyms | |
Description | FUNCTION: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of substrate tRNAs . Required for the correct positioning of the substrate tRNA for methylation . Required to suppress amino acid starvation-induced autophagy . Enhances the STK11/LKB1-induced cell growth suppression activity . . |
Accessions | E9PDU5 C9K020 ENST00000395474.7 ENST00000419837.1 ENST00000415265.6 V9GZ65 Q9NNW5 A0A087X295 ENST00000448293.5 ENST00000438660.5 E5RFX3 V9GYU1 ENST00000452875.5 F8WE36 ENST00000491365.1 ENST00000610967.4 Q6PKC6 ENST00000420783.7 ENST00000627177.1 ENST00000608424.6 Q6AZD6 ENST00000429900.6 ENST00000489427.1 C9JFP6 E9PBK6 V9GZ48 |