Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| B cell | 27 studies | 26% ± 9% | |
| macrophage | 25 studies | 31% ± 16% | |
| naive B cell | 16 studies | 25% ± 5% | |
| endothelial cell | 15 studies | 29% ± 12% | |
| memory B cell | 14 studies | 23% ± 4% | |
| classical monocyte | 14 studies | 24% ± 8% | |
| non-classical monocyte | 14 studies | 28% ± 10% | |
| monocyte | 11 studies | 28% ± 9% | |
| oligodendrocyte | 10 studies | 29% ± 10% | |
| pericyte | 10 studies | 24% ± 10% | |
| myeloid cell | 10 studies | 30% ± 10% | |
| microglial cell | 10 studies | 42% ± 18% | |
| fibroblast | 9 studies | 26% ± 9% | |
| astrocyte | 8 studies | 32% ± 14% | |
| adipocyte | 7 studies | 27% ± 6% | |
| oligodendrocyte precursor cell | 7 studies | 30% ± 14% | |
| epithelial cell | 6 studies | 34% ± 15% | |
| dendritic cell | 6 studies | 29% ± 8% | |
| GABAergic neuron | 5 studies | 37% ± 17% | |
| precursor B cell | 5 studies | 35% ± 8% | |
| smooth muscle cell | 5 studies | 22% ± 3% | |
| plasmacytoid dendritic cell | 5 studies | 20% ± 5% | |
| capillary endothelial cell | 4 studies | 18% ± 1% | |
| pro-B cell | 4 studies | 37% ± 9% | |
| immature B cell | 4 studies | 32% ± 9% | |
| mononuclear phagocyte | 4 studies | 30% ± 9% | |
| lymphocyte | 4 studies | 23% ± 7% | |
| type I pneumocyte | 4 studies | 19% ± 5% | |
| glutamatergic neuron | 4 studies | 46% ± 18% | |
| endothelial cell of lymphatic vessel | 4 studies | 34% ± 7% | |
| interneuron | 4 studies | 35% ± 21% | |
| glomerular endothelial cell | 3 studies | 20% ± 1% | |
| retinal ganglion cell | 3 studies | 22% ± 6% | |
| ciliated cell | 3 studies | 26% ± 2% | |
| alveolar macrophage | 3 studies | 39% ± 12% | |
| neuron | 3 studies | 29% ± 16% | |
| abnormal cell | 3 studies | 27% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2875.58 | 1445 / 1445 | 100% | 32.21 | 183 / 183 |
| lung | 100% | 4174.02 | 578 / 578 | 100% | 23.80 | 1155 / 1155 |
| breast | 100% | 4300.00 | 459 / 459 | 100% | 25.94 | 1115 / 1118 |
| kidney | 100% | 2745.08 | 89 / 89 | 100% | 32.96 | 898 / 901 |
| thymus | 100% | 3633.57 | 653 / 653 | 99% | 20.82 | 601 / 605 |
| prostate | 100% | 3072.37 | 245 / 245 | 99% | 20.10 | 498 / 502 |
| ovary | 100% | 4021.26 | 180 / 180 | 99% | 11.97 | 425 / 430 |
| adrenal gland | 100% | 3911.07 | 258 / 258 | 99% | 20.11 | 227 / 230 |
| brain | 99% | 1775.47 | 2604 / 2642 | 100% | 27.10 | 705 / 705 |
| uterus | 100% | 4129.10 | 170 / 170 | 98% | 18.18 | 451 / 459 |
| bladder | 100% | 3435.62 | 21 / 21 | 98% | 18.15 | 493 / 504 |
| liver | 100% | 2271.57 | 226 / 226 | 98% | 15.77 | 397 / 406 |
| pancreas | 99% | 2067.27 | 326 / 328 | 98% | 21.08 | 175 / 178 |
| stomach | 100% | 2260.23 | 358 / 359 | 98% | 23.29 | 280 / 286 |
| intestine | 100% | 3455.35 | 966 / 966 | 97% | 20.53 | 513 / 527 |
| skin | 100% | 3986.68 | 1809 / 1809 | 94% | 23.62 | 442 / 472 |
| blood vessel | 100% | 4081.83 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5341.30 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 18.91 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.56 | 1 / 1 |
| adipose | 100% | 4923.89 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 2192.43 | 799 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 22.91 | 28 / 29 |
| heart | 96% | 1748.45 | 826 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 88% | 3427.24 | 813 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 76% | 12.46 | 61 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0015031 | Biological process | protein transport |
| GO_0016197 | Biological process | endosomal transport |
| GO_0140591 | Biological process | nuclear envelope budding |
| GO_0034315 | Biological process | regulation of Arp2/3 complex-mediated actin nucleation |
| GO_0007032 | Biological process | endosome organization |
| GO_0031083 | Cellular component | BLOC-1 complex |
| GO_0031901 | Cellular component | early endosome membrane |
| GO_0071203 | Cellular component | WASH complex |
| GO_0005768 | Cellular component | endosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005515 | Molecular function | protein binding |
| Gene name | WASHC4 |
| Protein name | KIAA1033 protein WASH complex subunit 4 (Strumpellin and WASH-interacting protein) (SWIP) (WASH complex subunit SWIP) WASH complex subunit 4 |
| Synonyms | KIAA1033 |
| Description | FUNCTION: Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. . |
| Accessions | ENST00000551224.1 Q2M389 F8VYH7 F8VQX3 ENST00000550053.5 ENST00000547404.1 F8VNZ5 A0A087X256 B7ZKT9 ENST00000552203.1 ENST00000332180.10 [Q2M389-1] ENST00000620430.5 F8W1W1 ENST00000548195.5 R4GMM5 |