WASHC4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015031Biological processprotein transport
GO_0016197Biological processendosomal transport
GO_0140591Biological processnuclear envelope budding
GO_0034315Biological processregulation of Arp2/3 complex-mediated actin nucleation
GO_0007032Biological processendosome organization
GO_0031083Cellular componentBLOC-1 complex
GO_0031901Cellular componentearly endosome membrane
GO_0071203Cellular componentWASH complex
GO_0005768Cellular componentendosome
GO_0005654Cellular componentnucleoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameWASHC4
Protein nameKIAA1033 protein
WASH complex subunit 4 (Strumpellin and WASH-interacting protein) (SWIP) (WASH complex subunit SWIP)
WASH complex subunit 4
SynonymsKIAA1033
DescriptionFUNCTION: Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. .

AccessionsENST00000551224.1
Q2M389
F8VYH7
F8VQX3
ENST00000550053.5
ENST00000547404.1
F8VNZ5
A0A087X256
B7ZKT9
ENST00000552203.1
ENST00000332180.10 [Q2M389-1]
ENST00000620430.5
F8W1W1
ENST00000548195.5
R4GMM5