Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 4 studies | 19% ± 3% | |
| epithelial cell | 4 studies | 30% ± 11% | |
| endothelial cell | 4 studies | 23% ± 7% | |
| myofibroblast cell | 3 studies | 18% ± 2% | |
| pericyte | 3 studies | 18% ± 2% | |
| ciliated cell | 3 studies | 19% ± 1% | |
| macrophage | 3 studies | 17% ± 1% | |
| abnormal cell | 3 studies | 26% ± 6% | |
| fibroblast | 3 studies | 21% ± 4% |
Insufficient scRNA-seq data for expression of VPS72 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2042.14 | 1445 / 1445 | 100% | 75.71 | 183 / 183 |
| ovary | 100% | 1778.12 | 180 / 180 | 100% | 163.78 | 430 / 430 |
| skin | 100% | 1697.95 | 1809 / 1809 | 100% | 111.87 | 472 / 472 |
| uterus | 100% | 2102.34 | 170 / 170 | 100% | 124.43 | 459 / 459 |
| brain | 100% | 1907.89 | 2641 / 2642 | 100% | 138.49 | 705 / 705 |
| breast | 100% | 1731.03 | 459 / 459 | 100% | 123.90 | 1117 / 1118 |
| intestine | 100% | 1747.46 | 966 / 966 | 100% | 82.84 | 526 / 527 |
| thymus | 100% | 1571.72 | 653 / 653 | 100% | 87.12 | 603 / 605 |
| lung | 100% | 1417.52 | 576 / 578 | 100% | 105.63 | 1155 / 1155 |
| stomach | 100% | 1366.11 | 359 / 359 | 100% | 79.85 | 285 / 286 |
| prostate | 100% | 1956.56 | 245 / 245 | 100% | 92.88 | 500 / 502 |
| kidney | 100% | 1449.69 | 89 / 89 | 99% | 57.26 | 894 / 901 |
| bladder | 100% | 2349.05 | 21 / 21 | 99% | 111.09 | 500 / 504 |
| pancreas | 99% | 853.23 | 326 / 328 | 99% | 81.04 | 177 / 178 |
| liver | 100% | 676.30 | 225 / 226 | 99% | 70.98 | 402 / 406 |
| adrenal gland | 100% | 1466.66 | 258 / 258 | 96% | 67.44 | 221 / 230 |
| adipose | 100% | 1657.21 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1867.65 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 80.25 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 104.83 | 29 / 29 |
| muscle | 100% | 2598.70 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1698.71 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 86.05 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 53.55 | 1 / 1 |
| heart | 99% | 1103.64 | 855 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 1396.71 | 905 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_2000779 | Biological process | regulation of double-strand break repair |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0042981 | Biological process | regulation of apoptotic process |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0045815 | Biological process | transcription initiation-coupled chromatin remodeling |
| GO_1905168 | Biological process | positive regulation of double-strand break repair via homologous recombination |
| GO_0051726 | Biological process | regulation of cell cycle |
| GO_0035019 | Biological process | somatic stem cell population maintenance |
| GO_0000786 | Cellular component | nucleosome |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0035267 | Cellular component | NuA4 histone acetyltransferase complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0042393 | Molecular function | histone binding |
| GO_0140713 | Molecular function | histone chaperone activity |
| GO_0140849 | Molecular function | ATP-dependent H2AZ histone chaperone activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | VPS72 |
| Protein name | Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1) (Transcription factor-like 1) |
| Synonyms | YL1 TCFL1 |
| Description | FUNCTION: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. . |
| Accessions | ENST00000354473.4 [Q15906-2] ENST00000368892.9 [Q15906-1] Q15906 |
