USP6NL report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1903358Biological processregulation of Golgi organization
GO_0007030Biological processGolgi organization
GO_0048227Biological processplasma membrane to endosome transport
GO_1902017Biological processregulation of cilium assembly
GO_0043547Biological processpositive regulation of GTPase activity
GO_0019068Biological processvirion assembly
GO_0090630Biological processactivation of GTPase activity
GO_0035526Biological processretrograde transport, plasma membrane to Golgi
GO_0032588Cellular componenttrans-Golgi network membrane
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0031410Cellular componentcytoplasmic vesicle
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameUSP6NL
Protein nameUSP6 N-terminal like
USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)
USP6NL protein
SynonymsKIAA0019
DescriptionFUNCTION: Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. .

AccessionsQ92738
ENST00000379237.6
ENST00000277575.5 [Q92738-2]
ENST00000609853.1
V9GYH2
ENST00000609104.6 [Q92738-1]
X6RAB3
Q96FW8