TSSC4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000244Biological processspliceosomal tri-snRNP complex assembly
GO_0000387Biological processspliceosomal snRNP assembly
GO_0005682Cellular componentU5 snRNP
GO_0005681Cellular componentspliceosomal complex
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0044877Molecular functionprotein-containing complex binding
GO_0140313Molecular functionmolecular sequestering activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTSSC4
Protein nameU5 small nuclear ribonucleoprotein TSSC4
U5 small nuclear ribonucleoprotein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein)
Tumor suppressing subtransferable candidate 4
Synonyms
DescriptionFUNCTION: Protein associated with the U5 snRNP, during its maturation and its post-splicing recycling and which is required for spliceosomal tri-snRNP complex assembly in the nucleus . Has a molecular sequestering activity and transiently hinders SNRNP200 binding sites for constitutive splicing factors that intervene later during the assembly of the spliceosome and splicing . Together with its molecular sequestering activity, may also function as a molecular adapter and placeholder, coordinating the assembly of the U5 snRNP and its association with the U4/U6 di-snRNP . .

AccessionsQ9Y5U2
A6NCC9
E9PL88
C9JHT9
C9JDU0
ENST00000435795.5
ENST00000440813.1
E9PME3
C9JJV1
ENST00000437110.5
ENST00000451491.2 [Q9Y5U2-1]
ENST00000333256.11 [Q9Y5U2-1]
ENST00000380996.9 [Q9Y5U2-2]
ENST00000496468.1
ENST00000380992.5
ENST00000485682.6