Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 10 studies | 26% ± 7% | |
CD16-positive, CD56-dim natural killer cell, human | 6 studies | 19% ± 4% | |
natural killer cell | 6 studies | 21% ± 4% | |
classical monocyte | 5 studies | 24% ± 8% | |
epithelial cell | 5 studies | 33% ± 14% | |
endothelial cell of vascular tree | 5 studies | 20% ± 4% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 19% ± 2% | |
smooth muscle cell | 4 studies | 22% ± 3% | |
ciliated cell | 4 studies | 26% ± 6% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 3 studies | 18% ± 3% | |
B cell | 3 studies | 21% ± 2% | |
CD4-positive, alpha-beta T cell | 3 studies | 20% ± 6% | |
conventional dendritic cell | 3 studies | 28% ± 10% | |
non-classical monocyte | 3 studies | 30% ± 8% | |
pericyte | 3 studies | 20% ± 3% | |
fibroblast | 3 studies | 23% ± 5% | |
plasmacytoid dendritic cell | 3 studies | 22% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 1427.00 | 226 / 226 | 100% | 36.92 | 406 / 406 |
thymus | 100% | 1969.51 | 653 / 653 | 100% | 54.78 | 605 / 605 |
uterus | 100% | 2698.21 | 170 / 170 | 100% | 56.63 | 458 / 459 |
ovary | 100% | 1832.88 | 180 / 180 | 100% | 30.05 | 429 / 430 |
brain | 100% | 1282.75 | 2633 / 2642 | 100% | 56.05 | 705 / 705 |
adrenal gland | 100% | 1463.41 | 258 / 258 | 100% | 36.79 | 229 / 230 |
esophagus | 100% | 2256.87 | 1445 / 1445 | 99% | 26.88 | 182 / 183 |
kidney | 100% | 1631.55 | 89 / 89 | 99% | 32.22 | 896 / 901 |
pancreas | 100% | 990.61 | 328 / 328 | 99% | 48.26 | 177 / 178 |
prostate | 100% | 2552.43 | 245 / 245 | 99% | 61.40 | 498 / 502 |
skin | 100% | 2237.28 | 1809 / 1809 | 99% | 47.40 | 468 / 472 |
intestine | 100% | 2275.49 | 966 / 966 | 99% | 41.12 | 522 / 527 |
stomach | 100% | 1603.73 | 359 / 359 | 99% | 34.53 | 282 / 286 |
breast | 100% | 2013.38 | 459 / 459 | 99% | 43.84 | 1102 / 1118 |
bladder | 100% | 2561.38 | 21 / 21 | 98% | 46.84 | 495 / 504 |
lung | 100% | 1955.79 | 577 / 578 | 98% | 37.27 | 1136 / 1155 |
adipose | 100% | 2030.05 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2214.10 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 52.73 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 79.06 | 29 / 29 |
muscle | 100% | 2357.87 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2280.76 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 50.10 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 87.16 | 1 / 1 |
peripheral blood | 100% | 1665.90 | 927 / 929 | 0% | 0 | 0 / 0 |
heart | 99% | 1388.08 | 854 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000244 | Biological process | spliceosomal tri-snRNP complex assembly |
GO_0000387 | Biological process | spliceosomal snRNP assembly |
GO_0005682 | Cellular component | U5 snRNP |
GO_0005681 | Cellular component | spliceosomal complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0044877 | Molecular function | protein-containing complex binding |
GO_0140313 | Molecular function | molecular sequestering activity |
GO_0005515 | Molecular function | protein binding |
Gene name | TSSC4 |
Protein name | U5 small nuclear ribonucleoprotein TSSC4 U5 small nuclear ribonucleoprotein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) Tumor suppressing subtransferable candidate 4 |
Synonyms | |
Description | FUNCTION: Protein associated with the U5 snRNP, during its maturation and its post-splicing recycling and which is required for spliceosomal tri-snRNP complex assembly in the nucleus . Has a molecular sequestering activity and transiently hinders SNRNP200 binding sites for constitutive splicing factors that intervene later during the assembly of the spliceosome and splicing . Together with its molecular sequestering activity, may also function as a molecular adapter and placeholder, coordinating the assembly of the U5 snRNP and its association with the U4/U6 di-snRNP . . |
Accessions | Q9Y5U2 A6NCC9 E9PL88 C9JHT9 C9JDU0 ENST00000435795.5 ENST00000440813.1 E9PME3 C9JJV1 ENST00000437110.5 ENST00000451491.2 [Q9Y5U2-1] ENST00000333256.11 [Q9Y5U2-1] ENST00000380996.9 [Q9Y5U2-2] ENST00000496468.1 ENST00000380992.5 ENST00000485682.6 |