Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 14 studies | 25% ± 8% | |
| pericyte | 10 studies | 25% ± 5% | |
| oligodendrocyte precursor cell | 9 studies | 26% ± 11% | |
| regulatory T cell | 7 studies | 21% ± 7% | |
| astrocyte | 4 studies | 21% ± 4% | |
| Mueller cell | 4 studies | 34% ± 9% | |
| CD4-positive, alpha-beta T cell | 3 studies | 24% ± 3% | |
| glomerular endothelial cell | 3 studies | 22% ± 4% | |
| abnormal cell | 3 studies | 28% ± 1% | |
| T follicular helper cell | 3 studies | 22% ± 6% | |
| erythroblast | 3 studies | 27% ± 8% |
Insufficient scRNA-seq data for expression of TRIB2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 2700.40 | 2608 / 2642 | 100% | 118.17 | 702 / 705 |
| skin | 98% | 2513.95 | 1773 / 1809 | 100% | 268.56 | 471 / 472 |
| breast | 100% | 5755.24 | 459 / 459 | 94% | 48.53 | 1050 / 1118 |
| lung | 100% | 5928.03 | 578 / 578 | 89% | 44.58 | 1031 / 1155 |
| prostate | 100% | 5422.51 | 245 / 245 | 88% | 31.94 | 444 / 502 |
| thymus | 100% | 4006.43 | 652 / 653 | 87% | 27.51 | 526 / 605 |
| ovary | 100% | 13949.03 | 180 / 180 | 86% | 37.80 | 371 / 430 |
| adrenal gland | 100% | 8380.61 | 258 / 258 | 84% | 44.86 | 194 / 230 |
| uterus | 100% | 4954.81 | 170 / 170 | 84% | 46.20 | 387 / 459 |
| esophagus | 98% | 2609.47 | 1422 / 1445 | 83% | 35.60 | 151 / 183 |
| kidney | 100% | 6583.21 | 89 / 89 | 76% | 50.91 | 689 / 901 |
| pancreas | 81% | 2159.12 | 266 / 328 | 94% | 50.77 | 168 / 178 |
| bladder | 100% | 3785.24 | 21 / 21 | 65% | 33.36 | 330 / 504 |
| stomach | 100% | 4380.82 | 359 / 359 | 62% | 23.63 | 178 / 286 |
| intestine | 99% | 3566.87 | 955 / 966 | 54% | 18.88 | 285 / 527 |
| liver | 92% | 1490.64 | 209 / 226 | 46% | 16.15 | 188 / 406 |
| adipose | 100% | 5969.50 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 146.71 | 80 / 80 |
| spleen | 100% | 11620.34 | 241 / 241 | 0% | 0 | 0 / 0 |
| heart | 100% | 3835.79 | 860 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 3852.30 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 40.41 | 40 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 35.37 | 25 / 29 |
| muscle | 79% | 1035.07 | 638 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 34% | 506.27 | 312 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0032436 | Biological process | positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| GO_0045599 | Biological process | negative regulation of fat cell differentiation |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0006469 | Biological process | negative regulation of protein kinase activity |
| GO_0043405 | Biological process | regulation of MAP kinase activity |
| GO_0032693 | Biological process | negative regulation of interleukin-10 production |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0004860 | Molecular function | protein kinase inhibitor activity |
| GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
| GO_0055106 | Molecular function | ubiquitin-protein transferase regulator activity |
| GO_0031434 | Molecular function | mitogen-activated protein kinase kinase binding |
| GO_0031625 | Molecular function | ubiquitin protein ligase binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0000166 | Molecular function | nucleotide binding |
| GO_0004672 | Molecular function | protein kinase activity |
| Gene name | TRIB2 |
| Protein name | Tribbles homolog 2 (TRB-2) Tribbles homolog 2 |
| Synonyms | TRB2 |
| Description | FUNCTION: Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity). . FUNCTION: Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity. . FUNCTION: Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity. . |
| Accessions | ENST00000155926.9 B5MCX4 Q92519 ENST00000381465.2 ENST00000405331.3 F8WA18 |