Insufficient scRNA-seq data for expression of TRHR at single-cell level.
Insufficient scRNA-seq data for expression of TRHR at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 69% | 4.97 | 452 / 653 | 12% | 0.32 | 73 / 605 |
muscle | 72% | 3.17 | 580 / 803 | 0% | 0 | 0 / 0 |
breast | 64% | 2.28 | 293 / 459 | 1% | 0.02 | 7 / 1118 |
adipose | 62% | 2.44 | 741 / 1204 | 0% | 0 | 0 / 0 |
uterus | 59% | 2.09 | 100 / 170 | 0% | 0 | 0 / 459 |
lung | 56% | 1.97 | 325 / 578 | 1% | 0.02 | 10 / 1155 |
ovary | 54% | 1.69 | 98 / 180 | 0% | 0 | 0 / 430 |
heart | 54% | 2.13 | 461 / 861 | 0% | 0 | 0 / 0 |
spleen | 51% | 1.54 | 123 / 241 | 0% | 0 | 0 / 0 |
skin | 46% | 1.33 | 829 / 1809 | 0% | 0 | 0 / 472 |
blood vessel | 45% | 1.46 | 596 / 1335 | 0% | 0 | 0 / 0 |
bladder | 43% | 1.29 | 9 / 21 | 0% | 0.00 | 1 / 504 |
prostate | 43% | 1.27 | 105 / 245 | 0% | 0 | 0 / 502 |
esophagus | 42% | 1.34 | 600 / 1445 | 1% | 0.01 | 2 / 183 |
intestine | 42% | 1.19 | 409 / 966 | 0% | 0 | 0 / 527 |
stomach | 39% | 0.95 | 140 / 359 | 1% | 0.03 | 4 / 286 |
pancreas | 34% | 0.70 | 110 / 328 | 0% | 0 | 0 / 178 |
brain | 28% | 1.29 | 735 / 2642 | 1% | 0.01 | 4 / 705 |
adrenal gland | 28% | 0.59 | 73 / 258 | 0% | 0 | 0 / 230 |
kidney | 19% | 0.44 | 17 / 89 | 0% | 0.01 | 4 / 901 |
liver | 17% | 0.34 | 39 / 226 | 0% | 0 | 0 / 406 |
peripheral blood | 12% | 0.28 | 109 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007200 | Biological process | phospholipase C-activating G protein-coupled receptor signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0004997 | Molecular function | thyrotropin-releasing hormone receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | TRHR |
Protein name | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberin receptor) |
Synonyms | |
Description | FUNCTION: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway. . |
Accessions | P34981 ENST00000311762.2 ENST00000518632.2 |