TOGARAM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031116Biological processpositive regulation of microtubule polymerization
GO_1905515Biological processnon-motile cilium assembly
GO_0060271Biological processcilium assembly
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0035082Biological processaxoneme assembly
GO_0005930Cellular componentaxoneme
GO_0005929Cellular componentcilium
GO_0036064Cellular componentciliary basal body
GO_0005881Cellular componentcytoplasmic microtubule
GO_0005874Cellular componentmicrotubule
GO_0008017Molecular functionmicrotubule binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTOGARAM1
Protein nameTOG array regulator of axonemal microtubules protein 1 (Crescerin-1) (Protein FAM179B)
FAM179B protein
KIAA0423, isoform CRA_a (TOG array regulator of axonemal microtubules 1)
Alternative protein FAM179B
TOG array regulator of axonemal microtubules 1
SynonymsFAM179B
KIAA0423
hCG_20876
DescriptionFUNCTION: Involved in ciliogenesis . It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length . Interacts with microtubules and promotes microtubule polymerization via its HEAT repeat domains, especially those in TOG region 2 and 4 (By similarity). .

AccessionsL0R5A8
ENST00000361577.7 [Q9Y4F4-1]
H0YJ89
ENST00000556823.1
Q9Y4F4
G3XAE9
H0YIY7
Q6P183
ENST00000557250.1
ENST00000557423.5 [Q9Y4F4-3]
ENST00000555874.5
ENST00000361462.7
G3V3B1