Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 11 studies | 26% ± 10% | |
| macrophage | 7 studies | 27% ± 7% | |
| microglial cell | 7 studies | 25% ± 7% | |
| glutamatergic neuron | 6 studies | 45% ± 24% | |
| interneuron | 6 studies | 32% ± 20% | |
| epithelial cell | 6 studies | 32% ± 17% | |
| adipocyte | 6 studies | 19% ± 3% | |
| dendritic cell | 6 studies | 19% ± 4% | |
| GABAergic neuron | 6 studies | 38% ± 20% | |
| astrocyte | 6 studies | 33% ± 10% | |
| oligodendrocyte | 6 studies | 25% ± 8% | |
| neuron | 5 studies | 25% ± 9% | |
| oligodendrocyte precursor cell | 5 studies | 29% ± 10% | |
| ciliated cell | 4 studies | 24% ± 8% | |
| lymphocyte | 4 studies | 22% ± 7% | |
| fibroblast | 4 studies | 20% ± 5% | |
| monocyte | 4 studies | 24% ± 4% | |
| endothelial cell of lymphatic vessel | 4 studies | 22% ± 5% | |
| smooth muscle cell | 4 studies | 17% ± 1% | |
| type I pneumocyte | 4 studies | 23% ± 5% | |
| classical monocyte | 3 studies | 21% ± 1% | |
| hematopoietic precursor cell | 3 studies | 25% ± 6% | |
| myeloid cell | 3 studies | 22% ± 6% | |
| hepatocyte | 3 studies | 32% ± 22% | |
| abnormal cell | 3 studies | 27% ± 8% | |
| T cell | 3 studies | 18% ± 1% | |
| alveolar macrophage | 3 studies | 29% ± 9% | |
| pericyte | 3 studies | 21% ± 6% | |
| basal cell | 3 studies | 31% ± 21% | |
| goblet cell | 3 studies | 34% ± 20% | |
| transit amplifying cell | 3 studies | 38% ± 26% | |
| mast cell | 3 studies | 18% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3450.35 | 1445 / 1445 | 100% | 50.71 | 183 / 183 |
| intestine | 100% | 3289.18 | 966 / 966 | 100% | 56.53 | 527 / 527 |
| stomach | 100% | 2925.25 | 359 / 359 | 100% | 54.32 | 286 / 286 |
| uterus | 100% | 2938.83 | 170 / 170 | 100% | 52.97 | 459 / 459 |
| lung | 100% | 2748.81 | 578 / 578 | 100% | 53.75 | 1154 / 1155 |
| breast | 100% | 2822.80 | 459 / 459 | 100% | 63.48 | 1117 / 1118 |
| bladder | 100% | 3435.24 | 21 / 21 | 100% | 53.41 | 503 / 504 |
| prostate | 100% | 2604.10 | 245 / 245 | 100% | 41.77 | 501 / 502 |
| skin | 100% | 3859.57 | 1809 / 1809 | 100% | 76.36 | 471 / 472 |
| thymus | 100% | 3035.00 | 653 / 653 | 100% | 50.95 | 603 / 605 |
| kidney | 100% | 2453.07 | 89 / 89 | 100% | 43.38 | 897 / 901 |
| ovary | 100% | 2950.02 | 180 / 180 | 100% | 42.12 | 428 / 430 |
| brain | 100% | 2327.76 | 2629 / 2642 | 100% | 64.46 | 705 / 705 |
| pancreas | 99% | 1745.25 | 325 / 328 | 99% | 44.79 | 177 / 178 |
| adrenal gland | 100% | 3406.37 | 258 / 258 | 98% | 35.98 | 225 / 230 |
| liver | 100% | 1700.43 | 226 / 226 | 98% | 29.80 | 397 / 406 |
| adipose | 100% | 2905.24 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2921.70 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 55.69 | 29 / 29 |
| muscle | 100% | 3839.85 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3075.61 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 48.05 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 25.95 | 1 / 1 |
| peripheral blood | 99% | 4448.62 | 917 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 36.71 | 78 / 80 |
| heart | 96% | 1849.05 | 827 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006606 | Biological process | protein import into nucleus |
| GO_0005642 | Cellular component | annulate lamellae |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005635 | Cellular component | nuclear envelope |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0031267 | Molecular function | small GTPase binding |
| GO_0061608 | Molecular function | nuclear import signal receptor activity |
| Gene name | TNPO3 |
| Protein name | Transportin 3 Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR) |
| Synonyms | IPO12 |
| Description | FUNCTION: Importin, which transports target proteins into the nucleus . Specifically mediates the nuclear import of splicing factor serine/arginine (SR) proteins, such as RBM4, SFRS1 and SFRS2, by recognizing phosphorylated SR domains . Also mediates the nuclear import of serine/arginine (SR) protein CPSF6, independently of CPSF6 phosphorylation . The nuclear import process is regulated by the small GTPase Ran that partitions between cytoplasm and nucleus in the predominantly GDP- and GTP-bound form, respectively . Importin associates with target cargo proteins in the cytoplasm, and the competitive binding of GTP-bound Ran induces the release of cargos in the nucleus . .; FUNCTION: (Microbial infection) Involved in immunodeficiency virus (HIV-1) infection by importing the pre-integration complex (PIC) into the nucleus . Required for a nuclear maturation step of HIV-1 prior to integration . . |
| Accessions | E9PFH4 C9J7E5 ENST00000471234.5 [Q9Y5L0-5] ENST00000471166.1 ENST00000627585.2 Q9Y5L0 ENST00000482320.5 ENST00000265388.10 [Q9Y5L0-2] |