TNN | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of TNN at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	99%	1226.31	454 / 459	81%	8.53	904 / 1118
thymus	90%	315.60	585 / 653	31%	1.20	188 / 605
adipose	96%	604.10	1160 / 1204	0%	0	0 / 0
liver	71%	85.48	160 / 226	22%	0.53	91 / 406
spleen	76%	96.57	183 / 241	0%	0	0 / 0
skin	58%	350.77	1052 / 1809	14%	1.10	64 / 472
lung	44%	53.74	253 / 578	18%	0.64	212 / 1155
brain	5%	3.45	127 / 2642	49%	1.34	348 / 705
pancreas	3%	2.31	9 / 328	51%	1.58	91 / 178
stomach	28%	39.90	100 / 359	24%	1.34	70 / 286
intestine	40%	61.89	382 / 966	11%	0.31	60 / 527
kidney	24%	23.69	21 / 89	22%	0.64	197 / 901
esophagus	23%	19.28	335 / 1445	18%	0.87	33 / 183
heart	28%	32.19	239 / 861	0%	0	0 / 0
uterus	4%	8.73	7 / 170	19%	1.32	87 / 459
prostate	5%	6.42	13 / 245	14%	0.33	68 / 502
bladder	5%	2.67	1 / 21	12%	1.10	61 / 504
adrenal gland	10%	9.28	26 / 258	5%	0.11	11 / 230
tonsil	0%	0	0 / 0	13%	0.21	6 / 45
peripheral blood	12%	21.53	115 / 929	0%	0	0 / 0
blood vessel	8%	9.36	103 / 1335	0%	0	0 / 0
ovary	0%	0	0 / 180	6%	0.15	27 / 430
eye	0%	0	0 / 0	3%	0.06	2 / 80
muscle	1%	1.07	10 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0010976	Biological process	positive regulation of neuron projection development
GO_0033689	Biological process	negative regulation of osteoblast proliferation
GO_0007160	Biological process	cell-matrix adhesion
GO_1903672	Biological process	positive regulation of sprouting angiogenesis
GO_0090090	Biological process	negative regulation of canonical Wnt signaling pathway
GO_0007409	Biological process	axonogenesis
GO_0030334	Biological process	regulation of cell migration
GO_0045668	Biological process	negative regulation of osteoblast differentiation
GO_1905899	Biological process	regulation of smooth muscle tissue development
GO_1903010	Biological process	regulation of bone development
GO_1990138	Biological process	neuron projection extension
GO_0030155	Biological process	regulation of cell adhesion
GO_0002076	Biological process	osteoblast development
GO_0070593	Biological process	dendrite self-avoidance
GO_2001223	Biological process	negative regulation of neuron migration
GO_0005615	Cellular component	extracellular space
GO_1990026	Cellular component	hippocampal mossy fiber expansion
GO_0043025	Cellular component	neuronal cell body
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0009986	Cellular component	cell surface
GO_0097442	Cellular component	CA3 pyramidal cell dendrite
GO_0090733	Cellular component	tenascin complex
GO_0042802	Molecular function	identical protein binding
GO_0005178	Molecular function	integrin binding

Gene name	TNN
Protein name	Tenascin-N (TN-N) (Tenascin-W) (TN-W) Tenascin N
Synonyms	TNW
Description	FUNCTION: Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (By similarity) . Involved in neurite outgrowth and cell migration in hippocampal explants (By similarity). During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling (By similarity). In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells . Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells . .
Accessions	ENST00000621086.1 Q9UQP3 A0A087WXC4 ENST00000239462.9

TNN report