TLX1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TLX1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TLX1 at tissue level.

III. Associated gene sets

GO_0048513Biological processanimal organ development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameTLX1
Protein nameT-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
T cell leukemia homeobox 1
SynonymsTCL3
HOX11
DescriptionFUNCTION: Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.

AccessionsENST00000370196.11 [P31314-1]
P31314
ENST00000467928.2 [P31314-2]
ENST00000463716.3
G3V1B7