THAP12 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0046983Molecular functionprotein dimerization activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameTHAP12
Protein nameProtein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor), isoform CRA_b (cDNA FLJ56857, highly similar to 52 kDa repressor of the inhibitor of theprotein kinase)
Protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12)
THAP domain containing 12
SynonymsDAP4
P52RIPK
hCG_2017355
THAP0
PRKRIR
DescriptionFUNCTION: Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.

AccessionsENST00000260045.8 [O43422-1]
ENST00000684059.1
A0A804HKT7
A0A804HL83
E9PSI2
A0A804HKY5
A0A804HKN8
Q2YDB3
O43422
B4DS64
ENST00000682046.1
A0A804HKR8
ENST00000528993.5
ENST00000684702.1
ENST00000682527.1
ENST00000683600.1
ENST00000682978.1