TGIF2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TGIF2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TGIF2 at tissue level.

III. Associated gene sets

GO_0010470Biological processregulation of gastrulation
GO_1902871Biological processpositive regulation of amacrine cell differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006355Biological processregulation of DNA-templated transcription
GO_0035881Biological processamacrine cell differentiation
GO_0038092Biological processnodal signaling pathway
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameTGIF2
Protein nameHomeobox protein TGIF2 (5'-TG-3'-interacting factor 2) (TGF-beta-induced transcription factor 2) (TGFB-induced factor 2)
TGFB induced factor homeobox 2
Synonyms
DescriptionFUNCTION: Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins. .

AccessionsU3KQS0
U3KQB5
ENST00000373872.9 [Q9GZN2-1]
H0YKN5
U3KQ25
ENST00000561398.1
Q9GZN2
ENST00000560025.1 [Q9GZN2-1]
ENST00000558028.5
ENST00000558465.1
ENST00000611732.4 [Q9GZN2-1]
ENST00000557885.1
ENST00000373874.6 [Q9GZN2-1]
ENST00000650844.1 [Q9GZN2-1]