TFDP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0008544Biological processepidermis development
GO_0070345Biological processnegative regulation of fat cell proliferation
GO_0051091Biological processpositive regulation of DNA-binding transcription factor activity
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0043276Biological processanoikis
GO_1900087Biological processpositive regulation of G1/S transition of mitotic cell cycle
GO_0006355Biological processregulation of DNA-templated transcription
GO_2000278Biological processregulation of DNA biosynthetic process
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0035189Cellular componentRb-E2F complex
GO_0005654Cellular componentnucleoplasm
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0140297Molecular functionDNA-binding transcription factor binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0019904Molecular functionprotein domain specific binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0000987Molecular functioncis-regulatory region sequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTFDP1
Protein nameTranscription factor Dp-1
Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1)
SynonymsDP1
DescriptionFUNCTION: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication . The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters . .

AccessionsQ5JSB6
Q14186
ENST00000408980.6
Q5JSB5
ENST00000453989.2
F5H452
ENST00000544902.5
ENST00000375370.10 [Q14186-1]