I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 21% ± 3% | |
| astrocyte | 4 studies | 23% ± 7% | |
| non-classical monocyte | 3 studies | 18% ± 3% | |
| dendritic cell | 3 studies | 23% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 21% ± 3% | |
| astrocyte | 4 studies | 23% ± 7% | |
| non-classical monocyte | 3 studies | 18% ± 3% | |
| dendritic cell | 3 studies | 23% ± 1% |
Insufficient scRNA-seq data for expression of TBC1D10A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 2496.71 | 245 / 245 | 99% | 7.63 | 499 / 502 |
| uterus | 100% | 1826.89 | 170 / 170 | 99% | 8.62 | 455 / 459 |
| skin | 100% | 3448.02 | 1809 / 1809 | 99% | 11.72 | 467 / 472 |
| esophagus | 100% | 2740.17 | 1445 / 1445 | 99% | 6.64 | 181 / 183 |
| ovary | 100% | 2188.91 | 180 / 180 | 99% | 6.14 | 425 / 430 |
| thymus | 100% | 2346.51 | 652 / 653 | 99% | 9.79 | 598 / 605 |
| bladder | 100% | 2125.10 | 21 / 21 | 99% | 7.99 | 497 / 504 |
| breast | 100% | 2659.48 | 459 / 459 | 98% | 7.73 | 1099 / 1118 |
| lung | 100% | 2597.66 | 577 / 578 | 98% | 7.79 | 1134 / 1155 |
| intestine | 100% | 1952.11 | 966 / 966 | 96% | 5.02 | 507 / 527 |
| stomach | 100% | 1468.15 | 359 / 359 | 96% | 4.24 | 275 / 286 |
| kidney | 100% | 2012.48 | 89 / 89 | 94% | 4.95 | 845 / 901 |
| brain | 92% | 909.62 | 2441 / 2642 | 99% | 9.85 | 699 / 705 |
| pancreas | 88% | 619.50 | 290 / 328 | 99% | 9.19 | 177 / 178 |
| liver | 99% | 1011.64 | 224 / 226 | 83% | 3.40 | 335 / 406 |
| adrenal gland | 100% | 1754.41 | 258 / 258 | 68% | 3.51 | 156 / 230 |
| adipose | 100% | 2307.77 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 8.07 | 29 / 29 |
| spleen | 100% | 2763.99 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 9.48 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.91 | 1 / 1 |
| blood vessel | 100% | 2427.19 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 1571.97 | 906 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 4.88 | 75 / 80 |
| heart | 90% | 683.76 | 778 / 861 | 0% | 0 | 0 / 0 |
| muscle | 32% | 168.41 | 254 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042147 | Biological process | retrograde transport, endosome to Golgi |
| GO_1902017 | Biological process | regulation of cilium assembly |
| GO_0045862 | Biological process | positive regulation of proteolysis |
| GO_0097202 | Biological process | activation of cysteine-type endopeptidase activity |
| GO_0090630 | Biological process | activation of GTPase activity |
| GO_0005902 | Cellular component | microvillus |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0030165 | Molecular function | PDZ domain binding |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005096 | Molecular function | GTPase activator activity |
| Gene name | TBC1D10A |
| Protein name | TBC1 domain family member 10A (TBC1 domain family, member 10A, isoform CRA_e) TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein) (Rab27A-GAP-alpha) TBC1 domain family, member 10A TBC1 domain family member 10A |
| Synonyms | EPI64 TBC1D10 hCG_41315 |
| Description | FUNCTION: Acts as a GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A. . |
| Accessions | B7ZVY9 Q9BXI6 A7E244 ENST00000215790.12 [Q9BXI6-1] ENST00000403362.5 ENST00000403477.7 [Q9BXI6-2] F8WCD1 F8WDN6 ENST00000437122.1 ENST00000433426.5 F8W9Y7 ENST00000393906.2 B5MD46 |
