TASP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0040029Biological processepigenetic regulation of gene expression
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0006508Biological processproteolysis
GO_0051604Biological processprotein maturation
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0042802Molecular functionidentical protein binding
GO_0004298Molecular functionthreonine-type endopeptidase activity

IV. Literature review

[source]
Gene nameTASP1
Protein nameThreonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta]
Taspase 1
SynonymsC20orf13
DescriptionFUNCTION: Protease responsible for KMT2A/MLL1 processing and activation . It also activates KMT2D/MLL2 (By similarity). Through substrate activation, it controls the expression of HOXA genes, and the expression of key cell cycle regulators including CCNA1, CCNB1, CCNE1 and CDKN2A (By similarity) . .

AccessionsQ5JWM4
H7BZ38
ENST00000434275.1
ENST00000455532.5
ENST00000337743.9 [Q9H6P5-1]
Q9H6P5