Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 9 studies | 27% ± 13% | |
fibroblast | 8 studies | 26% ± 7% | |
macrophage | 8 studies | 22% ± 9% | |
classical monocyte | 7 studies | 23% ± 8% | |
connective tissue cell | 7 studies | 26% ± 9% | |
pericyte | 7 studies | 26% ± 5% | |
smooth muscle cell | 7 studies | 20% ± 3% | |
non-classical monocyte | 6 studies | 27% ± 10% | |
neuron | 6 studies | 39% ± 21% | |
B cell | 5 studies | 22% ± 5% | |
conventional dendritic cell | 5 studies | 30% ± 7% | |
regulatory T cell | 5 studies | 18% ± 3% | |
ciliated cell | 5 studies | 29% ± 7% | |
myofibroblast cell | 4 studies | 19% ± 1% | |
epithelial cell | 4 studies | 36% ± 14% | |
endothelial cell of lymphatic vessel | 4 studies | 22% ± 5% | |
neural crest cell | 3 studies | 17% ± 0% | |
GABAergic neuron | 3 studies | 18% ± 1% | |
glutamatergic neuron | 3 studies | 26% ± 2% | |
natural killer cell | 3 studies | 18% ± 2% | |
enteroendocrine cell | 3 studies | 26% ± 12% | |
erythrocyte | 3 studies | 35% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 455.63 | 1445 / 1445 | 100% | 15.50 | 183 / 183 |
ovary | 100% | 675.51 | 180 / 180 | 100% | 36.55 | 430 / 430 |
uterus | 100% | 586.08 | 170 / 170 | 100% | 32.31 | 459 / 459 |
brain | 100% | 561.30 | 2640 / 2642 | 100% | 23.73 | 705 / 705 |
breast | 100% | 619.56 | 459 / 459 | 100% | 24.99 | 1117 / 1118 |
thymus | 100% | 419.89 | 652 / 653 | 100% | 30.05 | 605 / 605 |
prostate | 100% | 439.56 | 245 / 245 | 100% | 18.16 | 501 / 502 |
kidney | 100% | 415.98 | 89 / 89 | 100% | 16.50 | 899 / 901 |
lung | 100% | 370.82 | 576 / 578 | 100% | 22.26 | 1155 / 1155 |
bladder | 100% | 482.33 | 21 / 21 | 99% | 26.93 | 499 / 504 |
intestine | 100% | 499.89 | 966 / 966 | 99% | 16.56 | 521 / 527 |
adrenal gland | 100% | 298.10 | 258 / 258 | 99% | 16.07 | 227 / 230 |
stomach | 99% | 317.24 | 356 / 359 | 99% | 15.73 | 284 / 286 |
skin | 100% | 379.78 | 1805 / 1809 | 98% | 14.72 | 464 / 472 |
liver | 96% | 206.79 | 217 / 226 | 97% | 14.85 | 393 / 406 |
pancreas | 85% | 132.64 | 278 / 328 | 99% | 20.00 | 177 / 178 |
adipose | 100% | 640.21 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 527.51 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 29.16 | 29 / 29 |
spleen | 100% | 447.34 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 22.70 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 33.39 | 1 / 1 |
peripheral blood | 99% | 398.14 | 924 / 929 | 0% | 0 | 0 / 0 |
muscle | 99% | 319.95 | 796 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 291.17 | 850 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 95% | 11.50 | 76 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010596 | Biological process | negative regulation of endothelial cell migration |
GO_1905048 | Biological process | regulation of metallopeptidase activity |
GO_0061564 | Biological process | axon development |
GO_0006508 | Biological process | proteolysis |
GO_0009306 | Biological process | protein secretion |
GO_0031397 | Biological process | negative regulation of protein ubiquitination |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005576 | Cellular component | extracellular region |
GO_0045177 | Cellular component | apical part of cell |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
GO_0016504 | Molecular function | peptidase activator activity |
GO_0008017 | Molecular function | microtubule binding |
Gene name | SVBP |
Protein name | Small vasohibin-binding protein (Coiled coil domain-containing protein 23) |
Synonyms | CCDC23 |
Description | FUNCTION: Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin . This activity is critical for spindle function and accurate chromosome segregation during mitosis since microtubule detyronisation regulates mitotic spindle length and postioning . Also required to enhance the solubility and secretion of VASH1 and VASH2 . Plays a role in axon and excitatory synapse formation . . |
Accessions | ENST00000372522.5 Q8N300 ENST00000372521.9 |