SUPT20H report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043484Biological processregulation of RNA splicing
GO_0006282Biological processregulation of DNA repair
GO_0006914Biological processautophagy
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0007369Biological processgastrulation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000124Cellular componentSAGA complex
GO_0070461Cellular componentSAGA-type complex
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003712Molecular functiontranscription coregulator activity

IV. Literature review

[source]
Gene nameSUPT20H
Protein nameTranscription factor SPT20 homolog (p38-interacting protein) (p38IP)
SPT20 homolog, SAGA complex component
SPT20 homolog, SAGA complex component (cDNA FLJ54575, highly similar to Protein FAM48A)
SynonymsFAM48A
FP757
C13orf19
DescriptionFUNCTION: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail (By similarity). Required for starvation-induced ATG9A trafficking during autophagy. .

AccessionsENST00000490716.5
ENST00000497318.1
ENST00000495071.6
ENST00000356185.7 [Q8NEM7-2]
Q8NEM7
ENST00000464744.5 [Q8NEM7-2]
H7C5F9
C9JQS2
ENST00000469488.6
ENST00000475892.5 [Q8NEM7-3]
ENST00000350612.11 [Q8NEM7-1]
R4GND2
B4E2D5
ENST00000360252.8 [Q8NEM7-2]