Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| natural killer cell | 12 studies | 21% ± 8% | |
| CD16-positive, CD56-dim natural killer cell, human | 8 studies | 20% ± 3% | |
| CD16-negative, CD56-bright natural killer cell, human | 5 studies | 19% ± 3% | |
| non-classical monocyte | 3 studies | 18% ± 2% | |
| hematopoietic precursor cell | 3 studies | 23% ± 5% | |
| epithelial cell | 3 studies | 22% ± 8% | |
| basal cell | 3 studies | 23% ± 5% |
Insufficient scRNA-seq data for expression of STK26 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 890.73 | 1439 / 1445 | 99% | 45.19 | 182 / 183 |
| intestine | 100% | 889.44 | 965 / 966 | 98% | 37.38 | 516 / 527 |
| lung | 99% | 687.68 | 574 / 578 | 98% | 36.60 | 1137 / 1155 |
| stomach | 100% | 575.96 | 358 / 359 | 98% | 36.64 | 280 / 286 |
| bladder | 100% | 1184.05 | 21 / 21 | 96% | 32.50 | 484 / 504 |
| prostate | 100% | 1525.71 | 244 / 245 | 95% | 20.48 | 475 / 502 |
| uterus | 100% | 6335.85 | 170 / 170 | 93% | 34.99 | 428 / 459 |
| breast | 98% | 521.96 | 451 / 459 | 93% | 31.79 | 1037 / 1118 |
| pancreas | 91% | 246.07 | 298 / 328 | 95% | 20.49 | 169 / 178 |
| thymus | 98% | 318.09 | 640 / 653 | 76% | 13.07 | 457 / 605 |
| ovary | 87% | 305.87 | 157 / 180 | 82% | 13.32 | 352 / 430 |
| skin | 100% | 824.89 | 1806 / 1809 | 38% | 6.42 | 177 / 472 |
| liver | 89% | 240.43 | 202 / 226 | 44% | 6.12 | 178 / 406 |
| spleen | 100% | 1151.92 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 19.37 | 1 / 1 |
| blood vessel | 100% | 767.00 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 99% | 655.20 | 1193 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 2435.69 | 913 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 38.72 | 28 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 28.92 | 43 / 45 |
| kidney | 63% | 204.84 | 56 / 89 | 32% | 3.81 | 288 / 901 |
| adrenal gland | 36% | 77.68 | 92 / 258 | 56% | 7.04 | 128 / 230 |
| brain | 45% | 194.26 | 1196 / 2642 | 3% | 0.52 | 23 / 705 |
| heart | 34% | 75.73 | 294 / 861 | 0% | 0 | 0 / 0 |
| muscle | 7% | 12.47 | 55 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.30 | 3 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009267 | Biological process | cellular response to starvation |
| GO_0030033 | Biological process | microvillus assembly |
| GO_0034599 | Biological process | cellular response to oxidative stress |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0042981 | Biological process | regulation of apoptotic process |
| GO_0006915 | Biological process | apoptotic process |
| GO_0030336 | Biological process | negative regulation of cell migration |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0046777 | Biological process | protein autophosphorylation |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0012506 | Cellular component | vesicle membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0090443 | Cellular component | FAR/SIN/STRIPAK complex |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005829 | Cellular component | cytosol |
| GO_0071944 | Cellular component | cell periphery |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005798 | Cellular component | Golgi-associated vesicle |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0000287 | Molecular function | magnesium ion binding |
| GO_0004672 | Molecular function | protein kinase activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | STK26 |
| Protein name | non-specific serine/threonine protein kinase (EC 2.7.11.1) Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK) |
| Synonyms | MASK MST4 |
| Description | FUNCTION: Serine/threonine-protein kinase that acts as a mediator of cell growth . Modulates apoptosis . In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation . Phosphorylates ATG4B at 'Ser-383', thereby increasing autophagic flux . . |
| Accessions | Q499L9 ENST00000394335.6 [Q9P289-2] ENST00000496850.1 [Q9P289-3] Q8NBY1 B4E0Y9 ENST00000354719.10 ENST00000394334.7 [Q9P289-1] Q9P289 ENST00000481105.5 |
