Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 8 studies | 28% ± 10% | |
endothelial cell | 7 studies | 25% ± 8% | |
microglial cell | 6 studies | 22% ± 6% | |
oligodendrocyte | 6 studies | 26% ± 7% | |
epithelial cell | 5 studies | 28% ± 9% | |
astrocyte | 5 studies | 31% ± 9% | |
macrophage | 5 studies | 25% ± 2% | |
GABAergic neuron | 4 studies | 39% ± 15% | |
glutamatergic neuron | 4 studies | 48% ± 19% | |
oligodendrocyte precursor cell | 4 studies | 35% ± 10% | |
endothelial cell of lymphatic vessel | 4 studies | 18% ± 2% | |
fibroblast | 3 studies | 19% ± 2% | |
monocyte | 3 studies | 18% ± 2% | |
basal cell | 3 studies | 21% ± 5% | |
goblet cell | 3 studies | 34% ± 23% | |
adipocyte | 3 studies | 16% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1752.56 | 1445 / 1445 | 100% | 22.35 | 183 / 183 |
ovary | 100% | 2029.26 | 180 / 180 | 100% | 15.41 | 430 / 430 |
prostate | 100% | 2224.49 | 245 / 245 | 100% | 26.35 | 502 / 502 |
lung | 100% | 1868.76 | 577 / 578 | 100% | 20.38 | 1155 / 1155 |
breast | 100% | 2088.22 | 459 / 459 | 100% | 26.50 | 1116 / 1118 |
brain | 100% | 1318.05 | 2636 / 2642 | 100% | 21.58 | 704 / 705 |
pancreas | 100% | 1376.77 | 328 / 328 | 99% | 17.57 | 177 / 178 |
thymus | 100% | 2047.59 | 653 / 653 | 99% | 19.90 | 599 / 605 |
bladder | 100% | 2160.52 | 21 / 21 | 99% | 15.37 | 498 / 504 |
stomach | 100% | 1728.06 | 359 / 359 | 99% | 18.40 | 282 / 286 |
uterus | 100% | 2152.25 | 170 / 170 | 98% | 15.68 | 451 / 459 |
intestine | 100% | 1901.18 | 966 / 966 | 98% | 15.78 | 517 / 527 |
kidney | 100% | 1674.65 | 89 / 89 | 98% | 18.39 | 880 / 901 |
adrenal gland | 100% | 2097.59 | 258 / 258 | 95% | 15.27 | 218 / 230 |
skin | 100% | 2064.05 | 1808 / 1809 | 92% | 14.74 | 435 / 472 |
liver | 100% | 974.59 | 226 / 226 | 91% | 9.47 | 370 / 406 |
adipose | 100% | 1939.94 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2186.19 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 11.86 | 29 / 29 |
spleen | 100% | 1610.56 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.71 | 1 / 1 |
muscle | 100% | 1003.31 | 799 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 1247.45 | 851 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 16.60 | 44 / 45 |
peripheral blood | 81% | 1085.43 | 757 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 64% | 6.86 | 51 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0016236 | Biological process | macroautophagy |
GO_0036258 | Biological process | multivesicular body assembly |
GO_0043328 | Biological process | protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
GO_0090148 | Biological process | membrane fission |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0031901 | Cellular component | early endosome membrane |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0033565 | Cellular component | ESCRT-0 complex |
GO_0030139 | Cellular component | endocytic vesicle |
GO_0005737 | Cellular component | cytoplasm |
GO_0043130 | Molecular function | ubiquitin binding |
GO_0005515 | Molecular function | protein binding |
GO_0035091 | Molecular function | phosphatidylinositol binding |
Gene name | STAM2 |
Protein name | Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein) |
Synonyms | HBP |
Description | FUNCTION: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as a sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). . |
Accessions | O75886 ENST00000263904.5 [O75886-1] |