STAB1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of STAB1 at tissue level.

III. Associated gene sets

GO_0016525Biological processnegative regulation of angiogenesis
GO_0006954Biological processinflammatory response
GO_0007155Biological processcell adhesion
GO_0006898Biological processreceptor-mediated endocytosis
GO_0007267Biological processcell-cell signaling
GO_0042742Biological processdefense response to bacterium
GO_0030666Cellular componentendocytic vesicle membrane
GO_0005886Cellular componentplasma membrane
GO_0015035Molecular functionprotein-disulfide reductase activity
GO_0005041Molecular functionlow-density lipoprotein particle receptor activity
GO_0005509Molecular functioncalcium ion binding
GO_0030169Molecular functionlow-density lipoprotein particle binding
GO_0005515Molecular functionprotein binding
GO_0005540Molecular functionhyaluronic acid binding
GO_0005044Molecular functionscavenger receptor activity

IV. Literature review

[source]
Gene nameSTAB1
Protein nameStabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1) (MS-1 antigen)
Stabilin 1
SynonymsFEEL1
KIAA0246
DescriptionFUNCTION: Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. .

AccessionsH7C4W7
ENST00000321725.10 [Q9NY15-1]
Q9NY15
ENST00000469989.1