Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 39 studies | 44% ± 21% | |
classical monocyte | 19 studies | 30% ± 13% | |
endothelial cell | 14 studies | 28% ± 18% | |
monocyte | 10 studies | 26% ± 13% | |
microglial cell | 10 studies | 23% ± 6% | |
myeloid cell | 10 studies | 42% ± 11% | |
endothelial cell of lymphatic vessel | 8 studies | 20% ± 6% | |
mononuclear phagocyte | 5 studies | 37% ± 15% | |
endothelial cell of sinusoid | 4 studies | 61% ± 25% | |
conventional dendritic cell | 4 studies | 18% ± 2% | |
dendritic cell | 4 studies | 27% ± 8% | |
leukocyte | 3 studies | 23% ± 4% | |
non-classical monocyte | 3 studies | 31% ± 1% | |
tissue-resident macrophage | 3 studies | 62% ± 6% | |
vein endothelial cell | 3 studies | 19% ± 3% |
Insufficient scRNA-seq data for expression of STAB1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 16919.43 | 459 / 459 | 97% | 17.65 | 1083 / 1118 |
lung | 100% | 22824.82 | 577 / 578 | 95% | 19.18 | 1096 / 1155 |
adrenal gland | 100% | 28362.64 | 258 / 258 | 94% | 22.96 | 217 / 230 |
thymus | 97% | 10763.97 | 631 / 653 | 97% | 14.43 | 586 / 605 |
uterus | 99% | 10478.48 | 169 / 170 | 91% | 15.36 | 417 / 459 |
kidney | 97% | 12438.61 | 86 / 89 | 94% | 32.49 | 843 / 901 |
intestine | 99% | 16624.49 | 961 / 966 | 87% | 13.98 | 459 / 527 |
bladder | 100% | 18590.38 | 21 / 21 | 86% | 21.42 | 433 / 504 |
prostate | 96% | 10835.64 | 236 / 245 | 85% | 9.14 | 427 / 502 |
esophagus | 88% | 10714.10 | 1270 / 1445 | 91% | 14.75 | 166 / 183 |
stomach | 86% | 8438.39 | 307 / 359 | 91% | 16.60 | 261 / 286 |
liver | 77% | 9136.76 | 175 / 226 | 90% | 13.25 | 364 / 406 |
ovary | 73% | 6094.86 | 131 / 180 | 89% | 17.50 | 381 / 430 |
pancreas | 52% | 2941.34 | 169 / 328 | 97% | 22.80 | 173 / 178 |
skin | 41% | 2600.98 | 733 / 1809 | 93% | 19.90 | 439 / 472 |
brain | 19% | 994.88 | 496 / 2642 | 98% | 33.96 | 693 / 705 |
spleen | 100% | 83824.41 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.05 | 1 / 1 |
adipose | 100% | 31870.21 | 1203 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 13.96 | 42 / 45 |
heart | 91% | 8587.93 | 781 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 90% | 13662.69 | 1199 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 90% | 14.76 | 26 / 29 |
eye | 0% | 0 | 0 / 0 | 78% | 9.59 | 62 / 80 |
peripheral blood | 72% | 9010.62 | 668 / 929 | 0% | 0 | 0 / 0 |
muscle | 46% | 2406.59 | 366 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0016525 | Biological process | negative regulation of angiogenesis |
GO_0006954 | Biological process | inflammatory response |
GO_0007155 | Biological process | cell adhesion |
GO_0006898 | Biological process | receptor-mediated endocytosis |
GO_0007267 | Biological process | cell-cell signaling |
GO_0042742 | Biological process | defense response to bacterium |
GO_0030666 | Cellular component | endocytic vesicle membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0015035 | Molecular function | protein-disulfide reductase activity |
GO_0005041 | Molecular function | low-density lipoprotein particle receptor activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0030169 | Molecular function | low-density lipoprotein particle binding |
GO_0005515 | Molecular function | protein binding |
GO_0005540 | Molecular function | hyaluronic acid binding |
GO_0005044 | Molecular function | scavenger receptor activity |
Gene name | STAB1 |
Protein name | Stabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1) (MS-1 antigen) Stabilin 1 |
Synonyms | FEEL1 KIAA0246 |
Description | FUNCTION: Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. . |
Accessions | H7C4W7 ENST00000321725.10 [Q9NY15-1] Q9NY15 ENST00000469989.1 |