Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 16 studies | 38% ± 17% | |
oligodendrocyte precursor cell | 13 studies | 42% ± 20% | |
glutamatergic neuron | 10 studies | 47% ± 24% | |
GABAergic neuron | 7 studies | 48% ± 21% | |
mast cell | 7 studies | 43% ± 22% | |
interneuron | 5 studies | 49% ± 18% | |
retinal ganglion cell | 5 studies | 38% ± 14% | |
fibroblast | 5 studies | 18% ± 2% | |
Mueller cell | 5 studies | 29% ± 6% | |
neuron | 4 studies | 30% ± 8% | |
endothelial cell | 3 studies | 38% ± 21% | |
GABAergic interneuron | 3 studies | 30% ± 5% | |
T follicular helper cell | 3 studies | 18% ± 2% | |
ependymal cell | 3 studies | 55% ± 14% | |
granule cell | 3 studies | 25% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 11 studies | 37% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1501.18 | 2636 / 2642 | 99% | 10.94 | 701 / 705 |
prostate | 98% | 862.42 | 240 / 245 | 65% | 1.61 | 326 / 502 |
skin | 76% | 292.53 | 1372 / 1809 | 86% | 5.53 | 408 / 472 |
adrenal gland | 98% | 678.11 | 253 / 258 | 51% | 1.88 | 118 / 230 |
lung | 96% | 645.15 | 554 / 578 | 37% | 0.88 | 433 / 1155 |
uterus | 99% | 692.49 | 168 / 170 | 23% | 0.67 | 107 / 459 |
breast | 71% | 413.61 | 327 / 459 | 48% | 1.59 | 542 / 1118 |
bladder | 100% | 1244.33 | 21 / 21 | 17% | 0.38 | 85 / 504 |
esophagus | 84% | 600.36 | 1217 / 1445 | 28% | 0.64 | 51 / 183 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.60 | 1 / 1 |
intestine | 88% | 806.86 | 850 / 966 | 7% | 0.15 | 38 / 527 |
thymus | 75% | 232.53 | 488 / 653 | 19% | 0.46 | 115 / 605 |
ovary | 63% | 165.94 | 114 / 180 | 11% | 0.22 | 49 / 430 |
stomach | 59% | 235.71 | 213 / 359 | 14% | 0.23 | 41 / 286 |
spleen | 71% | 186.67 | 172 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 69% | 227.28 | 925 / 1335 | 0% | 0 | 0 / 0 |
heart | 66% | 292.80 | 568 / 861 | 0% | 0 | 0 / 0 |
adipose | 63% | 234.10 | 764 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 56% | 1.37 | 25 / 45 |
lymph node | 0% | 0 | 0 / 0 | 48% | 1.62 | 14 / 29 |
kidney | 24% | 78.69 | 21 / 89 | 14% | 0.26 | 122 / 901 |
pancreas | 1% | 1.40 | 3 / 328 | 16% | 0.30 | 29 / 178 |
eye | 0% | 0 | 0 / 0 | 10% | 0.15 | 8 / 80 |
peripheral blood | 6% | 17.02 | 57 / 929 | 0% | 0 | 0 / 0 |
muscle | 3% | 7.16 | 28 / 803 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 2% | 0.04 | 7 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0050673 | Biological process | epithelial cell proliferation |
GO_0005975 | Biological process | carbohydrate metabolic process |
GO_0050679 | Biological process | positive regulation of epithelial cell proliferation |
GO_0006688 | Biological process | glycosphingolipid biosynthetic process |
GO_0034605 | Biological process | cellular response to heat |
GO_0009311 | Biological process | oligosaccharide metabolic process |
GO_0006491 | Biological process | N-glycan processing |
GO_0006486 | Biological process | protein glycosylation |
GO_0000139 | Cellular component | Golgi membrane |
GO_0016020 | Cellular component | membrane |
GO_0003828 | Molecular function | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity |
GO_0008373 | Molecular function | sialyltransferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ST8SIA1 |
Protein name | Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (EC 2.4.3.8) (Alpha-2,8-sialyltransferase 8A) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Sialyltransferase 8A) (SIAT8-A) (Sialyltransferase St8Sia I) (ST8SiaI) ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (ST8SIA1 protein) ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
Synonyms | SIAT8A SIAT8 |
Description | FUNCTION: Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3; gangliosides are a subfamily of complex glycosphingolipds that contain one or more residues of sialic acid . Can catalyze the addition of a second alpha-2,8-sialic acid to GD3 to form GT3 . Can use GM1b, GD1a and GT1b as acceptor substrates to synthesize GD1c, GT1a and GQ1b respectively . Can synthesize unusual tetra- and pentasialylated lactosylceramide derivatives identified as GQ3 (II3Neu5Ac4-Gg2Cer) and GP3 (II3Neu5Ac5-Gg2Cer) in breast cancer cells . . |
Accessions | F8WCS8 ENST00000540824.5 Q92185 Q86X71 ENST00000541868.1 ENST00000396037.9 [Q92185-1] H0YFU1 H0YGV9 ENST00000404299.3 ENST00000538256.1 ENST00000261197.7 [Q92185-2] ENST00000381424.3 H0YG41 |