Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 31 studies | 55% ± 24% | |
oligodendrocyte | 15 studies | 61% ± 13% | |
microglial cell | 15 studies | 67% ± 17% | |
astrocyte | 12 studies | 33% ± 18% | |
endothelial cell of lymphatic vessel | 11 studies | 65% ± 28% | |
glutamatergic neuron | 10 studies | 39% ± 20% | |
GABAergic neuron | 9 studies | 39% ± 17% | |
neuron | 7 studies | 36% ± 20% | |
smooth muscle cell | 6 studies | 40% ± 20% | |
interneuron | 6 studies | 39% ± 15% | |
macrophage | 6 studies | 34% ± 21% | |
capillary endothelial cell | 6 studies | 46% ± 19% | |
endothelial cell of artery | 6 studies | 47% ± 24% | |
vein endothelial cell | 6 studies | 56% ± 23% | |
podocyte | 5 studies | 69% ± 25% | |
type I pneumocyte | 5 studies | 25% ± 8% | |
epithelial cell | 4 studies | 49% ± 3% | |
oligodendrocyte precursor cell | 4 studies | 24% ± 5% | |
B cell | 4 studies | 27% ± 6% | |
Mueller cell | 4 studies | 51% ± 19% | |
monocyte | 4 studies | 34% ± 10% | |
endothelial cell of sinusoid | 3 studies | 48% ± 12% | |
pericyte | 3 studies | 45% ± 13% | |
GABAergic interneuron | 3 studies | 29% ± 9% | |
glial cell | 3 studies | 36% ± 9% | |
endocardial cell | 3 studies | 66% ± 27% | |
mast cell | 3 studies | 20% ± 5% | |
glycinergic amacrine cell | 3 studies | 48% ± 14% | |
endothelial cell of vascular tree | 3 studies | 77% ± 12% | |
club cell | 3 studies | 28% ± 12% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 16 studies | 43% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 97% | 662.26 | 2560 / 2642 | 99% | 5.76 | 698 / 705 |
thymus | 100% | 1598.31 | 653 / 653 | 89% | 9.66 | 536 / 605 |
adrenal gland | 95% | 324.24 | 244 / 258 | 73% | 1.95 | 168 / 230 |
kidney | 100% | 1286.33 | 89 / 89 | 61% | 3.44 | 550 / 901 |
breast | 100% | 1364.25 | 457 / 459 | 51% | 1.02 | 571 / 1118 |
lung | 100% | 1220.07 | 576 / 578 | 37% | 0.89 | 425 / 1155 |
ovary | 92% | 264.75 | 165 / 180 | 44% | 1.32 | 191 / 430 |
intestine | 96% | 403.86 | 923 / 966 | 34% | 0.74 | 180 / 527 |
stomach | 81% | 271.65 | 291 / 359 | 46% | 1.07 | 132 / 286 |
uterus | 99% | 732.47 | 168 / 170 | 25% | 1.38 | 115 / 459 |
skin | 35% | 95.84 | 634 / 1809 | 84% | 7.81 | 396 / 472 |
esophagus | 76% | 317.17 | 1093 / 1445 | 39% | 1.01 | 71 / 183 |
bladder | 90% | 473.86 | 19 / 21 | 21% | 0.43 | 104 / 504 |
prostate | 81% | 268.70 | 199 / 245 | 24% | 0.34 | 122 / 502 |
adipose | 100% | 1501.85 | 1203 / 1204 | 0% | 0 | 0 / 0 |
heart | 95% | 460.71 | 817 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 87% | 336.19 | 1163 / 1335 | 0% | 0 | 0 / 0 |
spleen | 86% | 342.52 | 208 / 241 | 0% | 0 | 0 / 0 |
pancreas | 18% | 35.88 | 60 / 328 | 63% | 1.36 | 112 / 178 |
muscle | 63% | 175.84 | 508 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 58% | 489.33 | 542 / 929 | 0% | 0 | 0 / 0 |
liver | 30% | 76.76 | 68 / 226 | 20% | 0.35 | 81 / 406 |
lymph node | 0% | 0 | 0 / 0 | 17% | 0.23 | 5 / 29 |
tonsil | 0% | 0 | 0 / 0 | 13% | 0.19 | 6 / 45 |
eye | 0% | 0 | 0 / 0 | 5% | 0.07 | 4 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006687 | Biological process | glycosphingolipid metabolic process |
GO_0001574 | Biological process | ganglioside biosynthetic process |
GO_0009100 | Biological process | glycoprotein metabolic process |
GO_0019082 | Biological process | viral protein processing |
GO_0009311 | Biological process | oligosaccharide metabolic process |
GO_0006677 | Biological process | glycosylceramide metabolic process |
GO_0006486 | Biological process | protein glycosylation |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005654 | Cellular component | nucleoplasm |
GO_0047290 | Molecular function | alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity |
GO_0001665 | Molecular function | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity |
GO_0008373 | Molecular function | sialyltransferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ST6GALNAC3 |
Protein name | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (EC 2.4.3.7) (GalNAc alpha-2,6-sialyltransferase III) (ST6GalNAc III) (ST6GalNAcIII) (STY) (Sialyltransferase 7C) (SIAT7-C) |
Synonyms | SIAT7C UNQ2787/PRO7177 |
Description | FUNCTION: Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the GalNAc residue on the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequence of glycoproteins and glycolipids forming an alpha-2,6-linkage. Produces branched type disialyl structures by transfer of a sialyl group onto a GalNAc residue inside the backbone core chains. ST6GalNAcIII prefers glycolipids to glycoproteins, predominantly catalyzing the biosynthesis of ganglioside GD1alpha from GM1b . GD1alpha is a critical molecule in the communication and interaction between neuronal cells and their supportive cells, particularly in brain tissues, and functions as an adhesion molecule in the process of metastasis (By similarity). Sialylation of glycoproteins or glycosphingolipids is very important in tumor development, neuronal development, nerve repair, immunological processes and regulation of hormone sensitivity . . |
Accessions | Q8NDV1 ENST00000328299.4 [Q8NDV1-1] |