Insufficient scRNA-seq data for expression of SSTR4 at single-cell level.
Insufficient scRNA-seq data for expression of SSTR4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 71% | 23.58 | 1876 / 2642 | 6% | 0.10 | 40 / 705 |
lung | 42% | 4.25 | 244 / 578 | 1% | 0.03 | 13 / 1155 |
intestine | 24% | 1.56 | 228 / 966 | 0% | 0.01 | 1 / 527 |
spleen | 22% | 1.18 | 53 / 241 | 0% | 0 | 0 / 0 |
uterus | 21% | 2.08 | 36 / 170 | 0% | 0.00 | 1 / 459 |
stomach | 16% | 0.93 | 57 / 359 | 1% | 0.01 | 2 / 286 |
thymus | 14% | 0.77 | 90 / 653 | 0% | 0.00 | 2 / 605 |
skin | 11% | 0.79 | 201 / 1809 | 3% | 0.06 | 12 / 472 |
bladder | 10% | 0.38 | 2 / 21 | 1% | 0.01 | 4 / 504 |
prostate | 9% | 0.40 | 21 / 245 | 0% | 0 | 0 / 502 |
heart | 7% | 0.34 | 59 / 861 | 0% | 0 | 0 / 0 |
pancreas | 6% | 0.27 | 20 / 328 | 1% | 0.01 | 1 / 178 |
ovary | 6% | 0.37 | 11 / 180 | 0% | 0.02 | 2 / 430 |
esophagus | 5% | 0.25 | 67 / 1445 | 0% | 0 | 0 / 183 |
adrenal gland | 4% | 0.20 | 10 / 258 | 0% | 0.01 | 1 / 230 |
adipose | 4% | 0.20 | 43 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 3% | 0.15 | 30 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 3% | 0.17 | 42 / 1335 | 0% | 0 | 0 / 0 |
breast | 3% | 0.15 | 13 / 459 | 0% | 0 | 0 / 1118 |
muscle | 1% | 0.09 | 12 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
kidney | 1% | 0.04 | 1 / 89 | 0% | 0.00 | 1 / 901 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0071385 | Biological process | cellular response to glucocorticoid stimulus |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0038170 | Biological process | somatostatin signaling pathway |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007218 | Biological process | neuropeptide signaling pathway |
GO_0090238 | Biological process | positive regulation of arachidonic acid secretion |
GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
GO_0106072 | Biological process | negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0016477 | Biological process | cell migration |
GO_0030900 | Biological process | forebrain development |
GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
GO_0005886 | Cellular component | plasma membrane |
GO_0043005 | Cellular component | neuron projection |
GO_0042923 | Molecular function | neuropeptide binding |
GO_0004994 | Molecular function | somatostatin receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SSTR4 |
Protein name | Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) (SST4) |
Synonyms | |
Description | FUNCTION: Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells. |
Accessions | P31391 ENST00000255008.5 |