Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 24 studies | 29% ± 14% | |
microglial cell | 10 studies | 41% ± 14% | |
macrophage | 10 studies | 26% ± 12% | |
fibroblast | 9 studies | 24% ± 11% | |
endothelial cell of vascular tree | 8 studies | 24% ± 12% | |
endothelial cell of lymphatic vessel | 7 studies | 41% ± 15% | |
myeloid cell | 6 studies | 21% ± 5% | |
vein endothelial cell | 6 studies | 32% ± 13% | |
astrocyte | 5 studies | 30% ± 7% | |
epithelial cell | 4 studies | 31% ± 10% | |
lymphocyte | 4 studies | 21% ± 6% | |
GABAergic neuron | 4 studies | 43% ± 17% | |
glutamatergic neuron | 4 studies | 47% ± 17% | |
endothelial cell of artery | 4 studies | 20% ± 4% | |
interneuron | 4 studies | 39% ± 21% | |
oligodendrocyte | 4 studies | 22% ± 4% | |
adipocyte | 3 studies | 16% ± 0% | |
cardiac muscle cell | 3 studies | 18% ± 1% | |
monocyte | 3 studies | 19% ± 4% | |
smooth muscle cell | 3 studies | 22% ± 1% | |
oligodendrocyte precursor cell | 3 studies | 26% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 8 studies | 30% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3708.56 | 1445 / 1445 | 100% | 18.01 | 183 / 183 |
lung | 100% | 6975.80 | 578 / 578 | 99% | 15.86 | 1149 / 1155 |
skin | 100% | 4702.85 | 1807 / 1809 | 100% | 23.03 | 470 / 472 |
intestine | 100% | 4069.05 | 966 / 966 | 99% | 11.16 | 522 / 527 |
breast | 100% | 3410.88 | 458 / 459 | 99% | 14.24 | 1107 / 1118 |
thymus | 100% | 3849.15 | 653 / 653 | 99% | 14.45 | 596 / 605 |
stomach | 100% | 2592.52 | 358 / 359 | 99% | 12.64 | 282 / 286 |
uterus | 100% | 4489.36 | 170 / 170 | 98% | 12.26 | 450 / 459 |
kidney | 100% | 2912.88 | 89 / 89 | 97% | 11.98 | 877 / 901 |
ovary | 100% | 3203.26 | 180 / 180 | 97% | 11.21 | 418 / 430 |
bladder | 100% | 4191.14 | 21 / 21 | 97% | 11.69 | 489 / 504 |
prostate | 100% | 3612.96 | 245 / 245 | 97% | 9.26 | 485 / 502 |
brain | 97% | 3016.19 | 2572 / 2642 | 99% | 11.53 | 699 / 705 |
adrenal gland | 100% | 3088.89 | 258 / 258 | 96% | 12.26 | 220 / 230 |
pancreas | 95% | 1355.61 | 312 / 328 | 98% | 13.82 | 175 / 178 |
liver | 99% | 1776.62 | 224 / 226 | 82% | 5.96 | 333 / 406 |
adipose | 100% | 3988.88 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 4419.66 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 4830.36 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.91 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.32 | 1 / 1 |
blood vessel | 100% | 4363.42 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 3223.62 | 854 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 14.55 | 79 / 80 |
peripheral blood | 94% | 4330.84 | 876 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 90% | 9.42 | 26 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030837 | Biological process | negative regulation of actin filament polymerization |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0031915 | Biological process | positive regulation of synaptic plasticity |
GO_0098976 | Biological process | excitatory chemical synaptic transmission |
GO_2000463 | Biological process | positive regulation of excitatory postsynaptic potential |
GO_1904719 | Biological process | positive regulation of AMPA glutamate receptor clustering |
GO_0071318 | Biological process | cellular response to ATP |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0000902 | Biological process | cell morphogenesis |
GO_0051246 | Biological process | regulation of protein metabolic process |
GO_1904754 | Biological process | positive regulation of vascular associated smooth muscle cell migration |
GO_0030496 | Cellular component | midbody |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005886 | Cellular component | plasma membrane |
GO_0045202 | Cellular component | synapse |
GO_0030426 | Cellular component | growth cone |
GO_0005737 | Cellular component | cytoplasm |
GO_0032154 | Cellular component | cleavage furrow |
GO_0030027 | Cellular component | lamellipodium |
GO_0004721 | Molecular function | phosphoprotein phosphatase activity |
GO_0017018 | Molecular function | myosin phosphatase activity |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | SSH1 |
Protein name | protein-serine/threonine phosphatase (EC 3.1.3.16) Slingshot protein phosphatase 1 Protein phosphatase Slingshot homolog 1 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 1) (SSH-1L) (hSSH-1L) |
Synonyms | SSH1L KIAA1298 |
Description | FUNCTION: Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. . |
Accessions | Q8WYL5 ENST00000546433.5 ENST00000326470.9 [Q8WYL5-5] ENST00000548522.5 F8VS18 F8W1D9 H0YHR3 ENST00000546697.1 ENST00000326495.10 [Q8WYL5-1] ENST00000551165.5 [Q8WYL5-2] |