SRCAP | OmnibusX

Name	Number of supported studies	Average coverage
brain	5 studies	22% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	10089.39	1445 / 1445	94%	2.23	172 / 183
stomach	100%	8724.22	359 / 359	73%	1.38	208 / 286
ovary	100%	9472.41	180 / 180	68%	1.30	292 / 430
breast	100%	9262.33	459 / 459	66%	1.17	737 / 1118
intestine	100%	10933.57	966 / 966	55%	0.93	291 / 527
lung	100%	9022.92	578 / 578	55%	0.91	636 / 1155
skin	100%	9662.57	1809 / 1809	44%	0.62	206 / 472
prostate	100%	11312.22	245 / 245	43%	0.59	215 / 502
thymus	100%	12265.92	653 / 653	41%	0.56	250 / 605
brain	98%	5960.88	2595 / 2642	35%	0.48	247 / 705
kidney	100%	6990.31	89 / 89	31%	0.41	276 / 901
bladder	100%	9756.48	21 / 21	30%	0.47	151 / 504
uterus	100%	11672.51	170 / 170	28%	0.41	129 / 459
pancreas	100%	6428.66	327 / 328	17%	0.23	30 / 178
adrenal gland	100%	9203.43	258 / 258	14%	0.19	33 / 230
liver	100%	4421.71	226 / 226	6%	0.08	26 / 406
adipose	100%	8214.89	1204 / 1204	0%	0	0 / 0
blood vessel	100%	8523.76	1335 / 1335	0%	0	0 / 0
muscle	100%	7082.37	803 / 803	0%	0	0 / 0
spleen	100%	12185.23	241 / 241	0%	0	0 / 0
heart	99%	5962.09	851 / 861	0%	0	0 / 0
peripheral blood	95%	5780.31	882 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	44%	0.66	20 / 45
lymph node	0%	0	0 / 0	34%	0.43	10 / 29
eye	0%	0	0 / 0	20%	0.25	16 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0006338	Biological process	chromatin remodeling
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0006355	Biological process	regulation of DNA-templated transcription
GO_0000812	Cellular component	Swr1 complex
GO_0000786	Cellular component	nucleosome
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0032991	Cellular component	protein-containing complex
GO_0005654	Cellular component	nucleoplasm
GO_0005794	Cellular component	Golgi apparatus
GO_0016604	Cellular component	nuclear body
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0004386	Molecular function	helicase activity
GO_0042393	Molecular function	histone binding
GO_0005524	Molecular function	ATP binding
GO_0140658	Molecular function	ATP-dependent chromatin remodeler activity
GO_0004402	Molecular function	histone acetyltransferase activity
GO_0003713	Molecular function	transcription coactivator activity
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity

Gene name	SRCAP
Protein name	Helicase SRCAP Snf2 related CREBBP activator protein SRCAP protein Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator)
Synonyms	KIAA0309
Description	FUNCTION: Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription. .
Accessions	Q6ZRS2 G1UI29 ENST00000483083.3 ENST00000411466.7 [Q6ZRS2-1] ENST00000262518.9 [Q6ZRS2-1] C9J4U4 ENST00000411466.7 A0A087X0E3 Q6P4A2 ENST00000706321.1 [Q6ZRS2-1]

SRCAP report