Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 15 studies | 27% ± 11% | |
| astrocyte | 10 studies | 31% ± 14% | |
| macrophage | 9 studies | 28% ± 8% | |
| glutamatergic neuron | 8 studies | 39% ± 23% | |
| oligodendrocyte | 8 studies | 28% ± 8% | |
| microglial cell | 7 studies | 26% ± 8% | |
| oligodendrocyte precursor cell | 6 studies | 28% ± 10% | |
| epithelial cell | 6 studies | 35% ± 15% | |
| dendritic cell | 6 studies | 23% ± 7% | |
| ciliated cell | 6 studies | 28% ± 9% | |
| GABAergic neuron | 6 studies | 39% ± 18% | |
| pericyte | 6 studies | 21% ± 6% | |
| interneuron | 5 studies | 38% ± 21% | |
| myeloid cell | 5 studies | 23% ± 9% | |
| monocyte | 5 studies | 29% ± 5% | |
| cardiac muscle cell | 4 studies | 20% ± 1% | |
| fibroblast | 4 studies | 18% ± 2% | |
| lymphocyte | 4 studies | 22% ± 6% | |
| abnormal cell | 4 studies | 25% ± 12% | |
| endothelial cell of lymphatic vessel | 4 studies | 27% ± 3% | |
| smooth muscle cell | 4 studies | 23% ± 3% | |
| neuron | 4 studies | 37% ± 14% | |
| classical monocyte | 3 studies | 23% ± 4% | |
| hematopoietic precursor cell | 3 studies | 24% ± 5% | |
| non-classical monocyte | 3 studies | 20% ± 5% | |
| granule cell | 3 studies | 19% ± 4% | |
| plasma cell | 3 studies | 28% ± 3% | |
| squamous epithelial cell | 3 studies | 38% ± 18% | |
| hepatocyte | 3 studies | 39% ± 27% | |
| ependymal cell | 3 studies | 29% ± 13% | |
| alveolar macrophage | 3 studies | 37% ± 9% | |
| plasmacytoid dendritic cell | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4692.60 | 1445 / 1445 | 100% | 67.20 | 183 / 183 |
| prostate | 100% | 4848.18 | 245 / 245 | 100% | 39.34 | 502 / 502 |
| skin | 100% | 6231.38 | 1809 / 1809 | 100% | 50.19 | 472 / 472 |
| stomach | 100% | 4169.76 | 359 / 359 | 100% | 49.63 | 286 / 286 |
| uterus | 100% | 5677.27 | 170 / 170 | 100% | 49.55 | 459 / 459 |
| breast | 100% | 4908.81 | 459 / 459 | 100% | 65.65 | 1117 / 1118 |
| brain | 100% | 5131.98 | 2639 / 2642 | 100% | 46.09 | 705 / 705 |
| thymus | 100% | 6184.63 | 653 / 653 | 100% | 40.99 | 604 / 605 |
| lung | 100% | 5249.33 | 578 / 578 | 100% | 53.84 | 1153 / 1155 |
| intestine | 100% | 5362.34 | 966 / 966 | 100% | 47.68 | 526 / 527 |
| bladder | 100% | 4749.95 | 21 / 21 | 100% | 41.74 | 503 / 504 |
| ovary | 100% | 5679.42 | 180 / 180 | 100% | 57.39 | 429 / 430 |
| liver | 100% | 3002.41 | 226 / 226 | 99% | 30.05 | 403 / 406 |
| pancreas | 100% | 3210.08 | 327 / 328 | 99% | 40.92 | 177 / 178 |
| kidney | 100% | 4664.66 | 89 / 89 | 99% | 37.07 | 893 / 901 |
| adrenal gland | 100% | 4144.71 | 258 / 258 | 97% | 27.64 | 222 / 230 |
| adipose | 100% | 4778.17 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 41.76 | 29 / 29 |
| muscle | 100% | 3770.60 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5816.19 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 51.59 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 27.06 | 1 / 1 |
| blood vessel | 100% | 3590.75 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 3707.01 | 854 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 5828.01 | 921 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 28.83 | 79 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006406 | Biological process | mRNA export from nucleus |
| GO_0000184 | Biological process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| GO_0035303 | Biological process | regulation of dephosphorylation |
| GO_0005829 | Cellular component | cytosol |
| GO_0005697 | Cellular component | telomerase holoenzyme complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0070034 | Molecular function | telomerase RNA binding |
| GO_0051721 | Molecular function | protein phosphatase 2A binding |
| GO_0042162 | Molecular function | telomeric DNA binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SMG7 |
| Protein name | Breast cancer-associated antigen SGA-56M (Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), isoform CRA_a) SMG7 nonsense mediated mRNA decay factor Nonsense-mediated mRNA decay factor SMG7 (SMG-7 homolog) (hSMG-7) Nonsense-mediated mRNA decay factor |
| Synonyms | hCG_39862 KIAA0250 C1orf16 SGA56M EST1C |
| Description | FUNCTION: Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. . FUNCTION: Plays a role in nonsense-mediated mRNA decay. . FUNCTION: Plays a role in nonsense-mediated mRNA decay. . FUNCTION: Plays a role in nonsense-mediated mRNA decay. . |
| Accessions | ENST00000347615.6 [Q92540-1] Q92540 E9PEK3 E9PBK2 ENST00000688051.1 E9PD50 D6R9J3 ENST00000419169.5 ENST00000507469.5 [Q92540-4] Q6TV06 ENST00000502375.1 ENST00000367537.7 ENST00000440812.7 A0A8I5KYV3 ENST00000685780.1 ENST00000515829.6 [Q92540-2] ENST00000508461.5 [Q92540-5] A0A8I5KSL3 ENST00000444547.6 B1ALB4 |