Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 14 studies | 28% ± 11% | |
smooth muscle cell | 13 studies | 25% ± 9% | |
pericyte | 11 studies | 28% ± 8% | |
astrocyte | 9 studies | 31% ± 10% | |
hepatocyte | 6 studies | 56% ± 22% | |
pancreatic A cell | 4 studies | 69% ± 18% | |
fibroblast | 4 studies | 21% ± 4% | |
epithelial cell | 4 studies | 27% ± 9% | |
retinal pigment epithelial cell | 4 studies | 35% ± 8% | |
mesothelial cell | 4 studies | 24% ± 6% | |
retinal cone cell | 4 studies | 24% ± 8% | |
cardiac muscle cell | 3 studies | 21% ± 4% | |
retinal rod cell | 3 studies | 19% ± 1% | |
luminal hormone-sensing cell of mammary gland | 3 studies | 23% ± 7% | |
muscle cell | 3 studies | 34% ± 15% | |
type II pneumocyte | 3 studies | 21% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 93% | 4893.84 | 228 / 245 | 97% | 37.50 | 488 / 502 |
liver | 100% | 25825.53 | 226 / 226 | 87% | 57.20 | 353 / 406 |
thymus | 100% | 6842.33 | 650 / 653 | 86% | 82.93 | 520 / 605 |
breast | 99% | 6807.52 | 455 / 459 | 70% | 126.19 | 780 / 1118 |
pancreas | 100% | 10745.56 | 328 / 328 | 61% | 22.05 | 109 / 178 |
ovary | 100% | 30199.71 | 180 / 180 | 44% | 14.22 | 190 / 430 |
uterus | 97% | 6504.05 | 165 / 170 | 32% | 12.32 | 145 / 459 |
lung | 78% | 2710.27 | 453 / 578 | 43% | 25.68 | 499 / 1155 |
kidney | 58% | 2472.04 | 52 / 89 | 53% | 20.66 | 478 / 901 |
bladder | 90% | 3610.19 | 19 / 21 | 21% | 7.77 | 105 / 504 |
esophagus | 75% | 2790.38 | 1078 / 1445 | 33% | 9.23 | 61 / 183 |
skin | 76% | 2922.96 | 1383 / 1809 | 25% | 6.35 | 119 / 472 |
muscle | 100% | 24106.10 | 803 / 803 | 0% | 0 | 0 / 0 |
adipose | 100% | 10605.82 | 1202 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 93% | 8402.23 | 1247 / 1335 | 0% | 0 | 0 / 0 |
stomach | 67% | 2179.77 | 240 / 359 | 19% | 6.40 | 54 / 286 |
adrenal gland | 66% | 2370.52 | 169 / 258 | 18% | 5.19 | 42 / 230 |
heart | 79% | 2691.23 | 679 / 861 | 0% | 0 | 0 / 0 |
brain | 18% | 480.27 | 480 / 2642 | 47% | 10.70 | 328 / 705 |
intestine | 50% | 1671.43 | 480 / 966 | 11% | 9.04 | 60 / 527 |
tonsil | 0% | 0 | 0 / 0 | 47% | 17.74 | 21 / 45 |
spleen | 37% | 980.26 | 88 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 16% | 2.25 | 13 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1903826 | Biological process | L-arginine transmembrane transport |
GO_0006865 | Biological process | amino acid transport |
GO_1903401 | Biological process | L-lysine transmembrane transport |
GO_0150104 | Biological process | transport across blood-brain barrier |
GO_1903352 | Biological process | L-ornithine transmembrane transport |
GO_0097638 | Biological process | L-arginine import across plasma membrane |
GO_0030054 | Cellular component | cell junction |
GO_0005886 | Cellular component | plasma membrane |
GO_0061459 | Molecular function | L-arginine transmembrane transporter activity |
GO_0015171 | Molecular function | amino acid transmembrane transporter activity |
GO_0000064 | Molecular function | L-ornithine transmembrane transporter activity |
GO_0015189 | Molecular function | L-lysine transmembrane transporter activity |
GO_0015174 | Molecular function | basic amino acid transmembrane transporter activity |
Gene name | SLC7A2 |
Protein name | Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Solute carrier family 7 member 2 Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 2, isoform CRA_d (Solute carrier family 7 member 2) |
Synonyms | CAT2 hCG_27753 ATRC2 |
Description | FUNCTION: Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine); the affinity for its substrates differs between isoforms created by alternative splicing . May play a role in classical or alternative activation of macrophages via its role in arginine transport (By similarity). .; FUNCTION: [Isoform 1]: Functions as a permease that mediates the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). Shows a much higher affinity for L-arginine and L-homoarginine than isoform 2. .; FUNCTION: [Isoform 2]: Functions as a low-affinity, high capacity permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). . |
Accessions | ENST00000640220.1 ENST00000640220.1 [P52569-1] ENST00000494857.6 [P52569-1] ENST00000398090.3 [P52569-2] ENST00000004531.14 [P52569-3] ENST00000522656.5 [P52569-1] A0A9H4ATX5 A0A1W2PR06 P52569 ENST00000470360.5 |