SLC7A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1903826Biological processL-arginine transmembrane transport
GO_0006865Biological processamino acid transport
GO_1903401Biological processL-lysine transmembrane transport
GO_0150104Biological processtransport across blood-brain barrier
GO_1903352Biological processL-ornithine transmembrane transport
GO_0097638Biological processL-arginine import across plasma membrane
GO_0030054Cellular componentcell junction
GO_0005886Cellular componentplasma membrane
GO_0061459Molecular functionL-arginine transmembrane transporter activity
GO_0015171Molecular functionamino acid transmembrane transporter activity
GO_0000064Molecular functionL-ornithine transmembrane transporter activity
GO_0015189Molecular functionL-lysine transmembrane transporter activity
GO_0015174Molecular functionbasic amino acid transmembrane transporter activity

IV. Literature review

[source]
Gene nameSLC7A2
Protein nameCationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2)
Solute carrier family 7 member 2
Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 2, isoform CRA_d (Solute carrier family 7 member 2)
SynonymsCAT2
hCG_27753
ATRC2
DescriptionFUNCTION: Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine); the affinity for its substrates differs between isoforms created by alternative splicing . May play a role in classical or alternative activation of macrophages via its role in arginine transport (By similarity). .; FUNCTION: [Isoform 1]: Functions as a permease that mediates the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). Shows a much higher affinity for L-arginine and L-homoarginine than isoform 2. .; FUNCTION: [Isoform 2]: Functions as a low-affinity, high capacity permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). .

AccessionsENST00000640220.1
ENST00000640220.1 [P52569-1]
ENST00000494857.6 [P52569-1]
ENST00000398090.3 [P52569-2]
ENST00000004531.14 [P52569-3]
ENST00000522656.5 [P52569-1]
A0A9H4ATX5
A0A1W2PR06
P52569
ENST00000470360.5