Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 22 studies | 64% ± 19% | |
epithelial cell of proximal tubule | 7 studies | 43% ± 27% | |
club cell | 6 studies | 33% ± 9% | |
GABAergic neuron | 6 studies | 36% ± 16% | |
glutamatergic neuron | 6 studies | 34% ± 18% | |
epithelial cell | 6 studies | 29% ± 12% | |
adipocyte | 6 studies | 26% ± 7% | |
mesothelial cell | 6 studies | 40% ± 15% | |
type II pneumocyte | 6 studies | 39% ± 11% | |
endothelial cell | 5 studies | 38% ± 21% | |
retinal ganglion cell | 5 studies | 47% ± 28% | |
respiratory goblet cell | 5 studies | 46% ± 19% | |
goblet cell | 5 studies | 25% ± 13% | |
retinal pigment epithelial cell | 4 studies | 34% ± 21% | |
cardiac muscle cell | 4 studies | 32% ± 5% | |
interneuron | 4 studies | 35% ± 13% | |
cholangiocyte | 3 studies | 50% ± 21% | |
pericyte | 3 studies | 28% ± 12% | |
hepatocyte | 3 studies | 42% ± 19% | |
oligodendrocyte precursor cell | 3 studies | 20% ± 4% | |
pancreatic ductal cell | 3 studies | 69% ± 16% | |
ependymal cell | 3 studies | 33% ± 13% | |
granule cell | 3 studies | 40% ± 6% | |
renal principal cell | 3 studies | 34% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 6197.46 | 2603 / 2642 | 98% | 111.58 | 690 / 705 |
prostate | 86% | 2941.18 | 211 / 245 | 97% | 151.72 | 486 / 502 |
kidney | 96% | 7045.82 | 85 / 89 | 86% | 57.28 | 776 / 901 |
pancreas | 100% | 21883.46 | 328 / 328 | 74% | 58.33 | 132 / 178 |
liver | 96% | 1758.88 | 218 / 226 | 37% | 11.44 | 151 / 406 |
thymus | 99% | 3038.30 | 647 / 653 | 29% | 8.61 | 173 / 605 |
lung | 73% | 927.31 | 421 / 578 | 31% | 7.66 | 356 / 1155 |
stomach | 70% | 1132.08 | 251 / 359 | 31% | 8.56 | 89 / 286 |
intestine | 51% | 2472.26 | 495 / 966 | 24% | 6.90 | 128 / 527 |
heart | 66% | 769.13 | 571 / 861 | 0% | 0 | 0 / 0 |
adipose | 45% | 701.03 | 546 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 39% | 452.22 | 517 / 1335 | 0% | 0 | 0 / 0 |
bladder | 19% | 308.52 | 4 / 21 | 10% | 1.66 | 49 / 504 |
esophagus | 6% | 48.74 | 80 / 1445 | 22% | 6.86 | 41 / 183 |
adrenal gland | 1% | 16.97 | 2 / 258 | 24% | 5.07 | 56 / 230 |
breast | 17% | 204.94 | 80 / 459 | 5% | 2.62 | 56 / 1118 |
skin | 4% | 45.45 | 80 / 1809 | 6% | 1.18 | 28 / 472 |
uterus | 1% | 6.52 | 1 / 170 | 10% | 1.89 | 44 / 459 |
ovary | 8% | 80.25 | 15 / 180 | 1% | 0.22 | 4 / 430 |
muscle | 4% | 33.08 | 34 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 8.66 | 7 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042391 | Biological process | regulation of membrane potential |
GO_0098656 | Biological process | monoatomic anion transmembrane transport |
GO_0055085 | Biological process | transmembrane transport |
GO_0150104 | Biological process | transport across blood-brain barrier |
GO_0006814 | Biological process | sodium ion transport |
GO_0015698 | Biological process | inorganic anion transport |
GO_0051453 | Biological process | regulation of intracellular pH |
GO_0015701 | Biological process | bicarbonate transport |
GO_0045821 | Biological process | positive regulation of glycolytic process |
GO_0035725 | Biological process | sodium ion transmembrane transport |
GO_0036376 | Biological process | sodium ion export across plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0009986 | Cellular component | cell surface |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0008509 | Molecular function | monoatomic anion transmembrane transporter activity |
GO_0015293 | Molecular function | symporter activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005452 | Molecular function | solute:inorganic anion antiporter activity |
GO_0005515 | Molecular function | protein binding |
GO_0008510 | Molecular function | sodium:bicarbonate symporter activity |
Gene name | SLC4A4 |
Protein name | Solute carrier family 4 member 4 Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1) Anion exchange protein |
Synonyms | NBC NBCE1 NBC1 |
Description | FUNCTION: Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. . FUNCTION: Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. . FUNCTION: Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. . |
Accessions | ENST00000340595.4 [Q9Y6R1-2] Q9Y6R1 ENST00000649996.1 [Q9Y6R1-1] A0A8V8TNB1 A0A1W2PRU6 A0A1W2PNW8 A5JJ20 ENST00000264485.11 [Q9Y6R1-1] ENST00000639096.1 ENST00000638464.1 ENST00000698522.1 ENST00000425175.5 [Q9Y6R1-5] ENST00000351898.10 [Q9Y6R1-4] ENST00000512686.5 [Q9Y6R1-3] |