Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 8 studies | 21% ± 5% | |
| myeloid cell | 6 studies | 24% ± 6% | |
| classical monocyte | 5 studies | 22% ± 5% | |
| mast cell | 5 studies | 28% ± 11% | |
| fibroblast | 4 studies | 28% ± 9% | |
| conventional dendritic cell | 3 studies | 23% ± 6% | |
| endothelial cell | 3 studies | 19% ± 1% | |
| erythroblast | 3 studies | 38% ± 14% | |
| endothelial cell of lymphatic vessel | 3 studies | 36% ± 3% | |
| erythrocyte | 3 studies | 35% ± 12% |
Insufficient scRNA-seq data for expression of SLC43A3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 100% | 5996.79 | 1802 / 1809 | 100% | 52.41 | 470 / 472 |
| liver | 100% | 13062.24 | 226 / 226 | 98% | 35.57 | 397 / 406 |
| ovary | 100% | 3050.56 | 180 / 180 | 97% | 17.11 | 418 / 430 |
| breast | 100% | 6888.39 | 459 / 459 | 97% | 17.28 | 1080 / 1118 |
| lung | 100% | 6735.48 | 578 / 578 | 93% | 21.95 | 1071 / 1155 |
| uterus | 99% | 3813.02 | 169 / 170 | 92% | 21.05 | 423 / 459 |
| thymus | 100% | 11718.88 | 652 / 653 | 90% | 24.34 | 543 / 605 |
| esophagus | 100% | 4405.07 | 1445 / 1445 | 86% | 13.20 | 157 / 183 |
| bladder | 100% | 4239.00 | 21 / 21 | 63% | 9.29 | 316 / 504 |
| intestine | 94% | 2822.15 | 905 / 966 | 64% | 9.23 | 335 / 527 |
| stomach | 70% | 2046.35 | 252 / 359 | 78% | 12.33 | 223 / 286 |
| pancreas | 51% | 829.57 | 166 / 328 | 92% | 13.54 | 163 / 178 |
| kidney | 51% | 1070.08 | 45 / 89 | 73% | 10.20 | 656 / 901 |
| adrenal gland | 90% | 2190.07 | 233 / 258 | 33% | 3.13 | 75 / 230 |
| prostate | 92% | 2227.28 | 226 / 245 | 26% | 1.46 | 131 / 502 |
| adipose | 100% | 8185.25 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 40.08 | 29 / 29 |
| spleen | 100% | 3249.01 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 4486.54 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 20.32 | 44 / 45 |
| heart | 96% | 2885.42 | 830 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 20.17 | 76 / 80 |
| peripheral blood | 84% | 5097.39 | 783 / 929 | 0% | 0 | 0 / 0 |
| brain | 6% | 81.70 | 164 / 2642 | 48% | 6.92 | 341 / 705 |
| muscle | 48% | 886.13 | 383 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0015908 | Biological process | fatty acid transport |
| GO_0042908 | Biological process | xenobiotic transport |
| GO_0015853 | Biological process | adenine transport |
| GO_1903716 | Biological process | guanine transmembrane transport |
| GO_0035344 | Biological process | hypoxanthine transport |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0042910 | Molecular function | xenobiotic transmembrane transporter activity |
| GO_0015207 | Molecular function | adenine transmembrane transporter activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0015245 | Molecular function | fatty acid transmembrane transporter activity |
| GO_0015208 | Molecular function | guanine transmembrane transporter activity |
| Gene name | SLC43A3 |
| Protein name | Solute carrier family 43 member 3 Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3) |
| Synonyms | PSEC0252 ENBT1 |
| Description | FUNCTION: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine . May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity). .; FUNCTION: [Isoform 1]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane . .; FUNCTION: [Isoform 2]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane . . |
| Accessions | ENST00000528187.5 ENST00000529113.5 E9PR94 ENST00000530005.5 E9PLF2 ENST00000533051.5 ENST00000533235.5 E9PKW3 E9PMZ1 ENST00000533524.5 [Q8NBI5-2] E9PL23 E9PJL3 ENST00000525474.5 ENST00000532795.5 E9PPE4 ENST00000525205.5 E9PLW1 ENST00000395123.6 [Q8NBI5-1] ENST00000529896.1 ENST00000524863.5 E9PR64 ENST00000533245.5 Q8NBI5 H0YD64 E9PLP1 ENST00000352187.5 [Q8NBI5-1] E9PJL1 ENST00000526621.5 E9PNM4 ENST00000529748.1 ENST00000529112.5 E9PJT6 ENST00000529554.5 [Q8NBI5-1] ENST00000530316.5 E9PS74 ENST00000395124.6 [Q8NBI5-1] E9PSH9 ENST00000529494.5 |
