Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 13 studies | 31% ± 15% | |
| microglial cell | 12 studies | 35% ± 13% | |
| endothelial cell | 11 studies | 36% ± 18% | |
| oligodendrocyte precursor cell | 11 studies | 34% ± 15% | |
| GABAergic neuron | 10 studies | 45% ± 27% | |
| glutamatergic neuron | 10 studies | 49% ± 25% | |
| macrophage | 10 studies | 30% ± 9% | |
| oligodendrocyte | 10 studies | 32% ± 11% | |
| retinal cone cell | 7 studies | 45% ± 14% | |
| interneuron | 6 studies | 51% ± 26% | |
| retina horizontal cell | 6 studies | 36% ± 16% | |
| neuron | 5 studies | 41% ± 17% | |
| retinal bipolar neuron | 5 studies | 48% ± 19% | |
| retinal ganglion cell | 5 studies | 31% ± 12% | |
| amacrine cell | 5 studies | 30% ± 12% | |
| retinal pigment epithelial cell | 5 studies | 59% ± 16% | |
| fibroblast | 5 studies | 28% ± 19% | |
| myeloid cell | 5 studies | 29% ± 11% | |
| granule cell | 4 studies | 24% ± 6% | |
| dendritic cell | 4 studies | 19% ± 2% | |
| retinal rod cell | 4 studies | 49% ± 14% | |
| GABAergic interneuron | 3 studies | 39% ± 2% | |
| B cell | 3 studies | 19% ± 4% | |
| GABAergic amacrine cell | 3 studies | 31% ± 12% | |
| Mueller cell | 3 studies | 31% ± 14% | |
| OFF-bipolar cell | 3 studies | 45% ± 24% | |
| ON-bipolar cell | 3 studies | 54% ± 22% | |
| glycinergic amacrine cell | 3 studies | 26% ± 8% | |
| rod bipolar cell | 3 studies | 72% ± 10% | |
| hepatocyte | 3 studies | 64% ± 22% | |
| endothelial cell of lymphatic vessel | 3 studies | 21% ± 6% | |
| monocyte | 3 studies | 24% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 7677.89 | 2641 / 2642 | 100% | 78.14 | 705 / 705 |
| adrenal gland | 100% | 30377.02 | 258 / 258 | 100% | 77.31 | 229 / 230 |
| skin | 99% | 2645.73 | 1792 / 1809 | 100% | 61.79 | 472 / 472 |
| prostate | 100% | 4544.22 | 245 / 245 | 98% | 26.43 | 490 / 502 |
| thymus | 100% | 7079.30 | 652 / 653 | 97% | 34.64 | 588 / 605 |
| esophagus | 98% | 2523.47 | 1417 / 1445 | 96% | 21.19 | 175 / 183 |
| lung | 100% | 4219.57 | 577 / 578 | 91% | 17.25 | 1048 / 1155 |
| liver | 100% | 9912.24 | 226 / 226 | 90% | 28.89 | 367 / 406 |
| breast | 100% | 3495.43 | 457 / 459 | 91% | 16.75 | 1012 / 1118 |
| pancreas | 92% | 1786.91 | 302 / 328 | 94% | 19.34 | 168 / 178 |
| ovary | 100% | 12370.33 | 180 / 180 | 85% | 15.30 | 366 / 430 |
| uterus | 100% | 4889.01 | 170 / 170 | 85% | 14.77 | 389 / 459 |
| bladder | 100% | 4713.19 | 21 / 21 | 84% | 21.54 | 421 / 504 |
| kidney | 90% | 2244.71 | 80 / 89 | 92% | 20.18 | 831 / 901 |
| stomach | 99% | 2554.16 | 357 / 359 | 72% | 11.51 | 207 / 286 |
| intestine | 100% | 3301.33 | 962 / 966 | 67% | 8.81 | 353 / 527 |
| spleen | 100% | 7206.16 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.23 | 1 / 1 |
| adipose | 100% | 3470.17 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3710.92 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 38.65 | 78 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 22.64 | 26 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 12.44 | 39 / 45 |
| heart | 82% | 1506.45 | 703 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 64% | 1542.76 | 593 / 929 | 0% | 0 | 0 / 0 |
| muscle | 15% | 192.88 | 122 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0015882 | Biological process | L-ascorbic acid transmembrane transport |
| GO_0008015 | Biological process | blood circulation |
| GO_1903861 | Biological process | positive regulation of dendrite extension |
| GO_0007155 | Biological process | cell adhesion |
| GO_0019852 | Biological process | L-ascorbic acid metabolic process |
| GO_0006814 | Biological process | sodium ion transport |
| GO_0006979 | Biological process | response to oxidative stress |
| GO_0071361 | Biological process | cellular response to ethanol |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005215 | Molecular function | transporter activity |
| GO_0008520 | Molecular function | L-ascorbate:sodium symporter activity |
| GO_0015229 | Molecular function | L-ascorbic acid transmembrane transporter activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SLC23A2 |
| Protein name | Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Nucleobase transporter-like 1 protein) (Sodium-dependent vitamin C transporter 2) (hSVCT2) (Yolk sac permease-like molecule 2) Solute carrier family 23 (Nucleobase transporters), member 2, isoform CRA_b (Testicular secretory protein Li 48) Solute carrier family 23 member 2 Sodium-dependent vitamin C transporter 2 variant II |
| Synonyms | KIAA0238 YSPL2 hCG_2020216 SVCT2 SLC23A1 NBTL1 |
| Description | FUNCTION: Sodium/ascorbate cotransporter . Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate . . |
| Accessions | Q4ZGM1 ENST00000338244.6 [Q9UGH3-1] ENST00000423430.1 A0A140VK48 Q9UGH3 ENST00000379333.5 [Q9UGH3-1] H0Y544 |