SFTPB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006665Biological processsphingolipid metabolic process
GO_0007585Biological processrespiratory gaseous exchange by respiratory system
GO_0009887Biological processanimal organ morphogenesis
GO_0045334Cellular componentclathrin-coated endocytic vesicle
GO_0097486Cellular componentmultivesicular body lumen
GO_0097208Cellular componentalveolar lamellar body
GO_0005764Cellular componentlysosome
GO_0005576Cellular componentextracellular region
GO_0042599Cellular componentlamellar body
GO_0005771Cellular componentmultivesicular body
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSFTPB
Protein namePulmonary surfactant-associated protein B (Pulmonary surfactant-associated proteolipid SPL(Phe))
Surfactant protein B
Pulmonary surfactant-associated protein B (SP-B) (18 kDa pulmonary-surfactant protein) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe))
SynonymsSFTP3
DescriptionFUNCTION: Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.

FUNCTION: Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. .

AccessionsP07988
ENST00000428225.5
U3KQT2
ENST00000393822.7
ENST00000409383.6
ENST00000519937.7
H0Y7V6
ENST00000494165.1