Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 22 studies | 34% ± 16% | |
fibroblast | 16 studies | 29% ± 14% | |
oligodendrocyte | 14 studies | 46% ± 15% | |
astrocyte | 13 studies | 32% ± 17% | |
type I pneumocyte | 11 studies | 43% ± 18% | |
GABAergic neuron | 10 studies | 47% ± 24% | |
glutamatergic neuron | 10 studies | 48% ± 25% | |
oligodendrocyte precursor cell | 10 studies | 35% ± 14% | |
adipocyte | 10 studies | 49% ± 13% | |
smooth muscle cell | 9 studies | 24% ± 10% | |
macrophage | 9 studies | 38% ± 13% | |
ciliated cell | 9 studies | 29% ± 11% | |
pericyte | 8 studies | 27% ± 13% | |
neuron | 7 studies | 45% ± 16% | |
epithelial cell | 7 studies | 32% ± 18% | |
endothelial cell of artery | 6 studies | 19% ± 3% | |
interneuron | 6 studies | 53% ± 23% | |
club cell | 6 studies | 28% ± 7% | |
retina horizontal cell | 6 studies | 63% ± 14% | |
endothelial cell of lymphatic vessel | 5 studies | 31% ± 13% | |
B cell | 5 studies | 22% ± 6% | |
dendritic cell | 5 studies | 23% ± 6% | |
type II pneumocyte | 5 studies | 39% ± 5% | |
granule cell | 4 studies | 25% ± 4% | |
myeloid cell | 4 studies | 23% ± 5% | |
amacrine cell | 4 studies | 23% ± 6% | |
connective tissue cell | 4 studies | 22% ± 8% | |
myofibroblast cell | 4 studies | 22% ± 5% | |
monocyte | 4 studies | 34% ± 4% | |
classical monocyte | 3 studies | 21% ± 6% | |
GABAergic interneuron | 3 studies | 40% ± 4% | |
glial cell | 3 studies | 23% ± 4% | |
microglial cell | 3 studies | 46% ± 10% | |
retinal ganglion cell | 3 studies | 29% ± 9% | |
abnormal cell | 3 studies | 23% ± 10% | |
ependymal cell | 3 studies | 32% ± 17% | |
adventitial cell | 3 studies | 28% ± 6% | |
alveolar macrophage | 3 studies | 38% ± 11% | |
respiratory goblet cell | 3 studies | 38% ± 11% | |
mucus secreting cell | 3 studies | 39% ± 7% | |
enteroendocrine cell | 3 studies | 18% ± 4% | |
basal cell | 3 studies | 23% ± 1% | |
secretory cell | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 7848.20 | 459 / 459 | 99% | 26.19 | 1112 / 1118 |
brain | 100% | 3576.56 | 2635 / 2642 | 100% | 19.70 | 702 / 705 |
lung | 99% | 5257.69 | 575 / 578 | 98% | 13.86 | 1129 / 1155 |
kidney | 99% | 2280.26 | 88 / 89 | 96% | 15.98 | 867 / 901 |
intestine | 99% | 3857.01 | 960 / 966 | 94% | 9.46 | 498 / 527 |
bladder | 100% | 6191.76 | 21 / 21 | 93% | 11.49 | 470 / 504 |
esophagus | 96% | 4456.55 | 1392 / 1445 | 96% | 12.81 | 176 / 183 |
stomach | 95% | 2939.28 | 342 / 359 | 97% | 10.92 | 276 / 286 |
uterus | 99% | 3262.90 | 168 / 170 | 92% | 12.15 | 424 / 459 |
prostate | 98% | 2552.87 | 241 / 245 | 92% | 6.88 | 461 / 502 |
skin | 97% | 2978.34 | 1763 / 1809 | 88% | 10.08 | 417 / 472 |
pancreas | 77% | 1122.24 | 251 / 328 | 98% | 16.73 | 175 / 178 |
thymus | 99% | 2571.58 | 647 / 653 | 75% | 4.77 | 456 / 605 |
ovary | 100% | 2698.04 | 180 / 180 | 67% | 4.31 | 287 / 430 |
adrenal gland | 71% | 916.85 | 182 / 258 | 74% | 5.31 | 171 / 230 |
liver | 30% | 359.74 | 68 / 226 | 80% | 6.55 | 324 / 406 |
blood vessel | 100% | 8505.88 | 1335 / 1335 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.17 | 1 / 1 |
adipose | 100% | 8393.37 | 1203 / 1204 | 0% | 0 | 0 / 0 |
spleen | 97% | 1680.66 | 233 / 241 | 0% | 0 | 0 / 0 |
heart | 92% | 2236.92 | 792 / 861 | 0% | 0 | 0 / 0 |
muscle | 82% | 1236.84 | 661 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 76% | 6.54 | 34 / 45 |
eye | 0% | 0 | 0 / 0 | 74% | 5.31 | 59 / 80 |
lymph node | 0% | 0 | 0 / 0 | 52% | 2.54 | 15 / 29 |
peripheral blood | 41% | 551.58 | 382 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1904878 | Biological process | negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel |
GO_0045111 | Cellular component | intermediate filament cytoskeleton |
GO_0034704 | Cellular component | calcium channel complex |
GO_0080025 | Molecular function | phosphatidylinositol-3,5-bisphosphate binding |
GO_0070300 | Molecular function | phosphatidic acid binding |
GO_0005545 | Molecular function | 1-phosphatidylinositol binding |
GO_0070273 | Molecular function | phosphatidylinositol-4-phosphate binding |
GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
GO_0031210 | Molecular function | phosphatidylcholine binding |
GO_0001786 | Molecular function | phosphatidylserine binding |
GO_0005515 | Molecular function | protein binding |
GO_0010314 | Molecular function | phosphatidylinositol-5-phosphate binding |
GO_0032266 | Molecular function | phosphatidylinositol-3-phosphate binding |
GO_0043325 | Molecular function | phosphatidylinositol-3,4-bisphosphate binding |
Gene name | SESTD1 |
Protein name | SEC14 and spectrin domain containing 1 SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein) (Protein Solo) Alternative protein SESTD1 SESTD1 protein |
Synonyms | SOLO |
Description | FUNCTION: May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1. . |
Accessions | Q86VW0 ENST00000428443.8 ENST00000446758.5 ENST00000435047.5 L8EBH0 Q7Z6D3 ENST00000335289.5 H7BXT9 C9J4X8 ENST00000440010.5 H0Y774 C9JHW6 |