Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 17 studies | 32% ± 14% | |
endothelial cell | 11 studies | 25% ± 6% | |
plasma cell | 9 studies | 37% ± 12% | |
macrophage | 9 studies | 25% ± 9% | |
pericyte | 8 studies | 25% ± 11% | |
microglial cell | 7 studies | 26% ± 11% | |
glutamatergic neuron | 7 studies | 33% ± 19% | |
type II pneumocyte | 6 studies | 25% ± 6% | |
myeloid cell | 5 studies | 21% ± 1% | |
epithelial cell | 5 studies | 31% ± 9% | |
goblet cell | 5 studies | 40% ± 26% | |
smooth muscle cell | 5 studies | 22% ± 4% | |
plasmablast | 4 studies | 43% ± 17% | |
adipocyte | 4 studies | 23% ± 6% | |
dendritic cell | 4 studies | 21% ± 3% | |
oligodendrocyte precursor cell | 4 studies | 24% ± 5% | |
connective tissue cell | 4 studies | 35% ± 18% | |
respiratory goblet cell | 4 studies | 34% ± 12% | |
club cell | 4 studies | 24% ± 10% | |
pancreatic A cell | 3 studies | 33% ± 15% | |
classical monocyte | 3 studies | 18% ± 1% | |
neuron | 3 studies | 18% ± 2% | |
mesothelial cell | 3 studies | 22% ± 1% | |
ciliated cell | 3 studies | 20% ± 1% | |
hepatocyte | 3 studies | 43% ± 17% | |
muscle cell | 3 studies | 26% ± 10% | |
adventitial cell | 3 studies | 23% ± 8% | |
myofibroblast cell | 3 studies | 23% ± 10% | |
monocyte | 3 studies | 20% ± 3% | |
astrocyte | 3 studies | 41% ± 17% | |
interneuron | 3 studies | 29% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 4359.53 | 577 / 578 | 100% | 28.84 | 1152 / 1155 |
pancreas | 100% | 3437.58 | 328 / 328 | 99% | 26.71 | 176 / 178 |
breast | 100% | 3405.15 | 459 / 459 | 99% | 39.03 | 1105 / 1118 |
stomach | 99% | 2543.40 | 357 / 359 | 99% | 25.34 | 284 / 286 |
intestine | 100% | 2967.40 | 966 / 966 | 98% | 23.31 | 519 / 527 |
esophagus | 99% | 2536.52 | 1436 / 1445 | 99% | 26.49 | 181 / 183 |
ovary | 100% | 2794.43 | 180 / 180 | 96% | 14.53 | 413 / 430 |
prostate | 100% | 2913.24 | 244 / 245 | 96% | 26.25 | 484 / 502 |
thymus | 100% | 4162.83 | 653 / 653 | 95% | 22.53 | 577 / 605 |
bladder | 100% | 3722.86 | 21 / 21 | 93% | 18.84 | 471 / 504 |
skin | 98% | 4916.57 | 1771 / 1809 | 91% | 18.97 | 431 / 472 |
uterus | 100% | 4342.68 | 170 / 170 | 86% | 16.72 | 395 / 459 |
liver | 100% | 4351.24 | 226 / 226 | 85% | 13.58 | 346 / 406 |
adrenal gland | 98% | 2143.10 | 254 / 258 | 83% | 14.80 | 190 / 230 |
kidney | 85% | 1360.54 | 76 / 89 | 83% | 13.23 | 747 / 901 |
adipose | 100% | 3676.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 6351.03 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 2996.80 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 90% | 1974.46 | 779 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 89% | 2742.88 | 827 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 87% | 17.00 | 39 / 45 |
lymph node | 0% | 0 | 0 / 0 | 83% | 11.76 | 24 / 29 |
brain | 32% | 320.58 | 844 / 2642 | 50% | 6.24 | 351 / 705 |
muscle | 38% | 371.31 | 303 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 16% | 1.33 | 13 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006886 | Biological process | intracellular protein transport |
GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
GO_0001701 | Biological process | in utero embryonic development |
GO_0090110 | Biological process | COPII-coated vesicle cargo loading |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0012507 | Cellular component | ER to Golgi transport vesicle membrane |
GO_0005829 | Cellular component | cytosol |
GO_0030127 | Cellular component | COPII vesicle coat |
GO_0070971 | Cellular component | endoplasmic reticulum exit site |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0000149 | Molecular function | SNARE binding |
GO_0005515 | Molecular function | protein binding |
GO_0008270 | Molecular function | zinc ion binding |
Gene name | SEC24D |
Protein name | SEC24D protein Protein transport protein Sec24D (SEC24-related protein D) SEC24 homolog D, COPII coat complex component (cDNA FLJ43974 fis, clone TESTI4018101, highly similar to Protein transport protein Sec24D) Uncharacterized protein SEC24D SEC24 homolog D, COPII coat complex component |
Synonyms | KIAA0755 |
Description | FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex . Plays a central role in cargo selection within the COPII complex and together with SEC24C may have a different specificity compared to SEC24A and SEC24B . May more specifically package GPI-anchored proteins through the cargo receptor TMED10 . May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 . . |
Accessions | O94855 E9PG84 D6RGJ5 E9PDM8 Q49AI3 ENST00000503683.1 ENST00000419654.6 ENST00000280551.11 [O94855-1] D6RBM1 ENST00000514561.5 Q4W5D3 ENST00000509818.5 ENST00000506622.5 ENST00000511481.5 E9PC44 D6RAE2 |