SCYL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008104Biological processprotein localization
GO_0006890Biological processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0006954Biological processinflammatory response
GO_0021522Biological processspinal cord motor neuron differentiation
GO_0048666Biological processneuron development
GO_0005813Cellular componentcentrosome
GO_0005801Cellular componentcis-Golgi network
GO_0030126Cellular componentCOPI vesicle coat
GO_0005829Cellular componentcytosol
GO_0005794Cellular componentGolgi apparatus
GO_0016020Cellular componentmembrane
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0045296Molecular functioncadherin binding
GO_0004713Molecular functionprotein tyrosine kinase activity
GO_0003677Molecular functionDNA binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameSCYL1
Protein nameN-terminal kinase-like protein (SCY1-like protein 1)
N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase)
SCY1 like pseudokinase 1
SynonymsGKLP
TRAP
HT019
NTKL
TEIF
CVAK90
TAPK
DescriptionFUNCTION: Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum . Involved in the maintenance of the Golgi apparatus morphology . Has no detectable kinase activity in vitro . .; FUNCTION: Isoform 6 acts as a transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region. .

AccessionsQ96KG9
H0YCI6
E9PPN3
ENST00000528545.1
ENST00000420247.6 [Q96KG9-2]
ENST00000524944.5
ENST00000270176.10 [Q96KG9-1]
ENST00000527009.5
E9PS17
ENST00000525364.5
E9PK59
ENST00000531601.1
H0YDH0
ENST00000533862.5 [Q96KG9-6]