SCG3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0033366Biological processprotein localization to secretory granule
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0030667Cellular componentsecretory granule membrane
GO_0030658Cellular componenttransport vesicle membrane
GO_0005576Cellular componentextracellular region
GO_0034774Cellular componentsecretory granule lumen
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameSCG3
Protein nameSecretogranin-3 (Secretogranin III) (SgIII)
Secretogranin-3 (Secretogranin III)
SynonymsUNQ2502/PRO5990
DescriptionFUNCTION: Member of the granin protein family that regulates the biogenesis of secretory granules . Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (By similarity). May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway . .

AccessionsQ8WXD2
ENST00000558709.1
H0YKC2
ENST00000542355.6 [Q8WXD2-2]
ENST00000220478.8 [Q8WXD2-1]