Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 11 studies | 19% ± 4% | |
CD16-positive, CD56-dim natural killer cell, human | 8 studies | 18% ± 3% | |
CD8-positive, alpha-beta T cell | 7 studies | 18% ± 3% | |
plasma cell | 6 studies | 27% ± 7% | |
CD16-negative, CD56-bright natural killer cell, human | 6 studies | 18% ± 3% | |
epithelial cell | 6 studies | 27% ± 12% | |
non-classical monocyte | 5 studies | 31% ± 14% | |
plasmablast | 4 studies | 44% ± 21% | |
B cell | 4 studies | 22% ± 2% | |
CD4-positive, alpha-beta T cell | 4 studies | 20% ± 3% | |
classical monocyte | 4 studies | 26% ± 8% | |
plasmacytoid dendritic cell | 4 studies | 24% ± 5% | |
conventional dendritic cell | 3 studies | 33% ± 12% | |
hematopoietic precursor cell | 3 studies | 22% ± 5% | |
mature NK T cell | 3 studies | 17% ± 2% | |
dendritic cell | 3 studies | 38% ± 15% | |
goblet cell | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 24% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2709.10 | 1445 / 1445 | 100% | 20.13 | 183 / 183 |
pancreas | 100% | 1420.43 | 328 / 328 | 100% | 16.62 | 178 / 178 |
ovary | 100% | 1538.24 | 180 / 180 | 100% | 22.74 | 429 / 430 |
liver | 100% | 1900.22 | 226 / 226 | 100% | 16.46 | 405 / 406 |
stomach | 100% | 1994.06 | 359 / 359 | 100% | 20.81 | 285 / 286 |
intestine | 100% | 1803.49 | 966 / 966 | 100% | 22.81 | 525 / 527 |
prostate | 100% | 2867.91 | 245 / 245 | 100% | 25.03 | 500 / 502 |
lung | 100% | 1796.35 | 577 / 578 | 100% | 21.87 | 1152 / 1155 |
uterus | 100% | 1861.34 | 170 / 170 | 100% | 25.91 | 457 / 459 |
thymus | 100% | 2082.86 | 653 / 653 | 100% | 15.99 | 602 / 605 |
skin | 100% | 4666.00 | 1809 / 1809 | 99% | 19.96 | 469 / 472 |
breast | 100% | 1635.44 | 459 / 459 | 99% | 19.06 | 1107 / 1118 |
bladder | 100% | 1626.48 | 21 / 21 | 99% | 23.53 | 499 / 504 |
kidney | 100% | 1583.17 | 89 / 89 | 98% | 11.66 | 886 / 901 |
adrenal gland | 100% | 1973.67 | 258 / 258 | 97% | 12.29 | 222 / 230 |
brain | 96% | 1079.41 | 2541 / 2642 | 100% | 13.14 | 704 / 705 |
adipose | 100% | 1436.46 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 14.72 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 21.74 | 29 / 29 |
spleen | 100% | 2744.03 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 26.47 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 23.21 | 1 / 1 |
muscle | 100% | 1624.44 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1667.71 | 1333 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 2267.94 | 924 / 929 | 0% | 0 | 0 / 0 |
heart | 96% | 1055.82 | 828 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0006412 | Biological process | translation |
GO_0018105 | Biological process | peptidyl-serine phosphorylation |
GO_0031929 | Biological process | TOR signaling |
GO_0045948 | Biological process | positive regulation of translational initiation |
GO_0046627 | Biological process | negative regulation of insulin receptor signaling pathway |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0042277 | Molecular function | peptide binding |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0004711 | Molecular function | ribosomal protein S6 kinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0004672 | Molecular function | protein kinase activity |
Gene name | RPS6KB2 |
Protein name | Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta) Ribosomal protein S6 kinase B2 Ribosomal protein S6 kinase (EC 2.7.11.1) |
Synonyms | STK14B |
Description | FUNCTION: Phosphorylates specifically ribosomal protein S6 . Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7 . . |
Accessions | R4GN47 Q9UBS0 ENST00000524934.5 ENST00000556575.5 ENST00000525996.7 G3V2F1 E9PIP7 ENST00000312629.10 [Q9UBS0-1] E9PQF6 ENST00000420069.3 Q9BRS0 ENST00000528964.5 [Q9UBS0-2] |