Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 16 studies | 82% ± 19% | |
endothelial cell | 11 studies | 34% ± 10% | |
astrocyte | 9 studies | 36% ± 17% | |
glutamatergic neuron | 5 studies | 29% ± 7% | |
epithelial cell | 5 studies | 26% ± 10% | |
type II pneumocyte | 5 studies | 19% ± 4% | |
neuron | 4 studies | 33% ± 13% | |
microglial cell | 4 studies | 40% ± 14% | |
GABAergic neuron | 4 studies | 27% ± 1% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 19% ± 1% | |
oligodendrocyte precursor cell | 3 studies | 38% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 7301.20 | 2642 / 2642 | 100% | 22.47 | 705 / 705 |
esophagus | 100% | 3860.21 | 1445 / 1445 | 100% | 13.19 | 183 / 183 |
intestine | 100% | 4429.27 | 966 / 966 | 100% | 17.32 | 527 / 527 |
kidney | 100% | 3295.71 | 89 / 89 | 100% | 12.19 | 901 / 901 |
ovary | 100% | 3797.08 | 180 / 180 | 100% | 17.82 | 430 / 430 |
skin | 100% | 3764.37 | 1809 / 1809 | 100% | 18.10 | 472 / 472 |
thymus | 100% | 3611.70 | 653 / 653 | 100% | 17.92 | 605 / 605 |
uterus | 100% | 4880.87 | 170 / 170 | 100% | 20.36 | 459 / 459 |
bladder | 100% | 4057.33 | 21 / 21 | 100% | 17.04 | 503 / 504 |
prostate | 100% | 4118.07 | 245 / 245 | 100% | 17.08 | 501 / 502 |
pancreas | 100% | 2296.80 | 327 / 328 | 100% | 16.07 | 178 / 178 |
lung | 100% | 3241.46 | 576 / 578 | 100% | 15.12 | 1155 / 1155 |
stomach | 100% | 2778.47 | 359 / 359 | 100% | 15.06 | 285 / 286 |
liver | 100% | 1814.00 | 226 / 226 | 100% | 10.54 | 404 / 406 |
breast | 100% | 3491.84 | 459 / 459 | 99% | 15.88 | 1112 / 1118 |
adrenal gland | 100% | 3338.95 | 258 / 258 | 99% | 14.13 | 227 / 230 |
adipose | 100% | 3228.80 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 16.84 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 19.74 | 29 / 29 |
spleen | 100% | 5055.82 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 18.73 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 16.82 | 1 / 1 |
muscle | 100% | 3285.60 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3094.42 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 2643.15 | 854 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 94% | 2337.64 | 869 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051865 | Biological process | protein autoubiquitination |
GO_0016567 | Biological process | protein ubiquitination |
GO_2000677 | Biological process | regulation of transcription regulatory region DNA binding |
GO_0003358 | Biological process | noradrenergic neuron development |
GO_0006513 | Biological process | protein monoubiquitination |
GO_0090263 | Biological process | positive regulation of canonical Wnt signaling pathway |
GO_0051091 | Biological process | positive regulation of DNA-binding transcription factor activity |
GO_0021904 | Biological process | dorsal/ventral neural tube patterning |
GO_0005652 | Cellular component | nuclear lamina |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0008013 | Molecular function | beta-catenin binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | RNF220 |
Protein name | RNF220 protein E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220) Ring finger protein 220 |
Synonyms | C1orf164 |
Description | FUNCTION: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling . Plays a critical role in the regulation of nuclear lamina . . |
Accessions | Q5TDE8 Q5TDE7 U3KPZ6 ENST00000335497.11 ENST00000355387.6 [Q5VTB9-1] ENST00000453863.5 ENST00000440132.2 H0Y7B1 Q5VTB9 Q9BWG1 ENST00000361799.7 [Q5VTB9-1] ENST00000488865.2 |