RGS6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0035556Biological processintracellular signal transduction
GO_0008277Biological processregulation of G protein-coupled receptor signaling pathway
GO_0043547Biological processpositive regulation of GTPase activity
GO_0009968Biological processnegative regulation of signal transduction
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0043005Cellular componentneuron projection
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005096Molecular functionGTPase activator activity
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRGS6
Protein nameRegulator of G protein signaling 6 (cDNA FLJ51839, highly similar to Regulator of G-protein signaling 6)
Regulator of G protein signaling 6
Regulator of G protein signaling 6 (cDNA FLJ53896, highly similar to Regulator of G-protein signaling 6)
Regulator of G-protein signaling 6 (Regulator of G-protein signalling 6, isoform CRA_i)
Regulator of G-protein signaling 6 (RGS6) (S914)
SynonymshCG_20660
DescriptionFUNCTION: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity . .

AccessionsENST00000553530.5 [P49758-4]
ENST00000406236.8 [P49758-13]
ENST00000355512.10 [P49758-16]
A0A0A0MRA9
A0A087WTW9
ENST00000644463.1
ENST00000434263.6
ENST00000402788.6
A0A2R8Y8A2
ENST00000556437.5 [P49758-3]
P49758
ENST00000404301.6 [P49758-15]
ENST00000555571.5 [P49758-4]
ENST00000553525.6 [P49758-3]
B7Z7N5
B7Z2N1
Q2M3K2
ENST00000407322.8 [P49758-14]
ENST00000554782.1 [P49758-12]
ENST00000554474.5 [P49758-5]
ENST00000343854.10
ENST00000622468.4