I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 4 studies | 22% ± 4% | |
| epithelial cell | 3 studies | 28% ± 8% | |
| ciliated cell | 3 studies | 18% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 4 studies | 22% ± 4% | |
| epithelial cell | 3 studies | 28% ± 8% | |
| ciliated cell | 3 studies | 18% ± 1% |
Insufficient scRNA-seq data for expression of RFX1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 2333.90 | 653 / 653 | 100% | 20.88 | 605 / 605 |
| uterus | 100% | 1781.02 | 170 / 170 | 100% | 15.15 | 459 / 459 |
| esophagus | 100% | 1176.54 | 1443 / 1445 | 100% | 20.99 | 183 / 183 |
| ovary | 100% | 1816.76 | 180 / 180 | 100% | 29.80 | 429 / 430 |
| intestine | 100% | 1268.20 | 966 / 966 | 99% | 15.23 | 524 / 527 |
| prostate | 100% | 1844.46 | 245 / 245 | 99% | 13.69 | 499 / 502 |
| skin | 100% | 1307.69 | 1809 / 1809 | 99% | 15.97 | 469 / 472 |
| stomach | 100% | 1118.87 | 359 / 359 | 99% | 16.37 | 284 / 286 |
| breast | 100% | 1500.15 | 459 / 459 | 99% | 14.94 | 1109 / 1118 |
| pancreas | 100% | 946.41 | 328 / 328 | 99% | 14.12 | 176 / 178 |
| bladder | 100% | 1271.90 | 21 / 21 | 99% | 12.99 | 497 / 504 |
| kidney | 100% | 1386.87 | 89 / 89 | 98% | 12.08 | 886 / 901 |
| adrenal gland | 100% | 1261.69 | 258 / 258 | 98% | 18.18 | 226 / 230 |
| lung | 100% | 1503.67 | 576 / 578 | 98% | 13.19 | 1137 / 1155 |
| brain | 98% | 1065.06 | 2589 / 2642 | 100% | 11.71 | 703 / 705 |
| liver | 100% | 963.98 | 226 / 226 | 95% | 7.40 | 384 / 406 |
| adipose | 100% | 1216.81 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 18.19 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 11.24 | 29 / 29 |
| spleen | 100% | 1965.03 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 13.73 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.43 | 1 / 1 |
| blood vessel | 100% | 1229.89 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 100% | 961.66 | 857 / 861 | 0% | 0 | 0 / 0 |
| muscle | 99% | 930.29 | 791 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 1224.89 | 914 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006955 | Biological process | immune response |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Gene name | RFX1 |
| Protein name | MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1) Regulatory factor X1 |
| Synonyms | |
| Description | FUNCTION: Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter. |
| Accessions | ENST00000672295.1 P22670 K7EIZ8 ENST00000588885.1 ENST00000254325.9 |
