REPIN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000191Biological processregulation of fatty acid transport
GO_0006260Biological processDNA replication
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0031965Cellular componentnuclear membrane
GO_0003723Molecular functionRNA binding
GO_0043035Molecular functionchromatin insulator sequence binding
GO_0043565Molecular functionsequence-specific DNA binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameREPIN1
Protein nameHCG1990708, isoform CRA_c (Replication initiator 1)
Replication initiator 1
Replication initiator 1 (60 kDa origin-specific DNA-binding protein) (60 kDa replication initiation region protein) (ATT-binding protein) (DHFR oribeta-binding protein RIP60) (Zinc finger protein 464)
SynonymsRIP60
hCG_1990708
ZNF464
tcag7.1235
DescriptionFUNCTION: Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending.

AccessionsA0A090N8Z2
ENST00000486714.2
ENST00000518514.1
ENST00000489432.7 [Q9BWE0-4]
E5RK52
ENST00000482680.1
ENST00000519397.1
ENST00000488943.1
ENST00000466559.1
A0A090N8H1
Q9BWE0
ENST00000522266.1
C9JYJ8
C9J7L2
ENST00000475514.5
ENST00000425389.2 [Q9BWE0-3]
C9J0L4
C9J590
C9JZE3
C9J7D4
ENST00000479668.5
E7EVL6
ENST00000467980.5
ENST00000397281.6 [Q9BWE0-3]
ENST00000444957.3 [Q9BWE0-3]