RELCH report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032367Biological processintracellular cholesterol transport
GO_0005802Cellular componenttrans-Golgi network
GO_0055037Cellular componentrecycling endosome

IV. Literature review

[source]
Gene nameRELCH
Protein nameRAB11-binding protein RELCH (LisH domain and HEAT repeat-containing protein KIAA1468) (RAB11 binding and LisH domain, coiled-coil and HEAT repeat-containing) (RAB11-binding protein containing LisH, coiled-coil, and HEAT repeats)
KIAA1468 protein (KIAA1468, isoform CRA_a)
RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
SynonymshCG_34283
KIAA1468
DescriptionFUNCTION: Regulates intracellular cholesterol distribution from recycling endosomes to the trans-Golgi network through interactions with RAB11 and OSBP . Functions in membrane tethering and promotes OSBP-mediated cholesterol transfer between RAB11-bound recycling endosomes and OSBP-bound Golgi-like membranes . .

AccessionsENST00000256858.10 [Q9P260-2]
A0A075B768
A0A075B785
Q9P260
ENST00000644646.2
A0A2R8Y566
ENST00000398130.6 [Q9P260-1]
ENST00000587725.5
Q96ES0
ENST00000588446.1