Name | Number of supported studies | Average coverage | |
---|---|---|---|
platelet | 8 studies | 32% ± 11% | |
astrocyte | 8 studies | 32% ± 11% | |
endothelial cell | 6 studies | 25% ± 4% | |
retinal rod cell | 6 studies | 18% ± 3% | |
Mueller cell | 6 studies | 42% ± 20% | |
smooth muscle cell | 5 studies | 23% ± 6% | |
epithelial cell | 5 studies | 32% ± 14% | |
fibroblast | 5 studies | 23% ± 7% | |
oligodendrocyte | 5 studies | 21% ± 4% | |
oligodendrocyte precursor cell | 5 studies | 41% ± 9% | |
pancreatic A cell | 4 studies | 39% ± 18% | |
myofibroblast cell | 4 studies | 22% ± 10% | |
retinal ganglion cell | 4 studies | 50% ± 25% | |
retinal pigment epithelial cell | 4 studies | 46% ± 17% | |
type B pancreatic cell | 3 studies | 44% ± 18% | |
pericyte | 3 studies | 21% ± 1% | |
retina horizontal cell | 3 studies | 27% ± 10% | |
retinal cone cell | 3 studies | 23% ± 6% | |
ciliated cell | 3 studies | 28% ± 11% | |
kidney loop of Henle epithelial cell | 3 studies | 19% ± 3% | |
luminal cell of prostate epithelium | 3 studies | 55% ± 4% | |
GABAergic neuron | 3 studies | 44% ± 7% | |
glutamatergic neuron | 3 studies | 51% ± 11% | |
pancreatic ductal cell | 3 studies | 55% ± 16% | |
megakaryocyte | 3 studies | 49% ± 6% | |
goblet cell | 3 studies | 20% ± 1% | |
hematopoietic stem cell | 3 studies | 24% ± 10% | |
neuron | 3 studies | 34% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 6580.48 | 258 / 258 | 100% | 72.21 | 230 / 230 |
bladder | 100% | 3860.24 | 21 / 21 | 100% | 38.89 | 504 / 504 |
brain | 100% | 4245.58 | 2642 / 2642 | 100% | 67.09 | 705 / 705 |
esophagus | 100% | 2910.72 | 1445 / 1445 | 100% | 38.62 | 183 / 183 |
intestine | 100% | 2800.64 | 966 / 966 | 100% | 35.88 | 527 / 527 |
prostate | 100% | 21164.78 | 245 / 245 | 100% | 854.38 | 502 / 502 |
thymus | 100% | 4427.92 | 653 / 653 | 100% | 51.76 | 605 / 605 |
breast | 100% | 2370.56 | 459 / 459 | 100% | 44.84 | 1117 / 1118 |
kidney | 100% | 4415.60 | 89 / 89 | 100% | 52.24 | 899 / 901 |
liver | 100% | 5316.12 | 226 / 226 | 100% | 49.99 | 405 / 406 |
pancreas | 100% | 1930.61 | 327 / 328 | 100% | 41.22 | 178 / 178 |
lung | 100% | 3443.12 | 578 / 578 | 100% | 37.87 | 1151 / 1155 |
uterus | 100% | 3576.94 | 170 / 170 | 100% | 40.10 | 457 / 459 |
stomach | 100% | 2521.01 | 359 / 359 | 99% | 31.67 | 284 / 286 |
skin | 100% | 3433.33 | 1809 / 1809 | 99% | 48.79 | 468 / 472 |
ovary | 100% | 2810.01 | 180 / 180 | 97% | 25.54 | 418 / 430 |
adipose | 100% | 2292.00 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 25.68 | 29 / 29 |
spleen | 100% | 2361.83 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 31.63 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 26.80 | 1 / 1 |
blood vessel | 100% | 2582.80 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 93% | 1268.20 | 805 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 81% | 20.88 | 65 / 80 |
peripheral blood | 79% | 1705.24 | 734 / 929 | 0% | 0 | 0 / 0 |
muscle | 37% | 277.02 | 298 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007601 | Biological process | visual perception |
GO_0001523 | Biological process | retinoid metabolic process |
GO_0042574 | Biological process | retinal metabolic process |
GO_0042572 | Biological process | retinol metabolic process |
GO_0110095 | Biological process | cellular detoxification of aldehyde |
GO_0001917 | Cellular component | photoreceptor inner segment |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0004745 | Molecular function | all-trans-retinol dehydrogenase (NAD+) activity |
GO_0102354 | Molecular function | 11-cis-retinol dehydrogenase activity |
GO_0033721 | Molecular function | aldehyde dehydrogenase (NADP+) activity |
GO_0005515 | Molecular function | protein binding |
GO_0016616 | Molecular function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
GO_0052650 | Molecular function | all-trans-retinol dehydrogenase (NADP+) activity |
Gene name | RDH11 |
Protein name | Retinol dehydrogenase 11 (All-trans and 9-cis), isoform CRA_a (cDNA FLJ32633 fis, clone SYNOV2000171, highly similar to Retinol dehydrogenase 11) Retinol dehydrogenase 11 Retinol dehydrogenase 11 isoform 2 Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short chain dehydrogenase/reductase family 7C member 1) Retinol dehydrogenase 11 isoform 1 |
Synonyms | SDR7C1 ARSDR1 CGI-82 hCG_21906 PSDR1 |
Description | FUNCTION: Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol . Exhibits a low reductive activity towards unsaturated medium-chain aldehydes such as cis -6-nonenal and no activity toward nonanal or 4-hydroxy-nonenal . Has no dehydrogenase activity towards steroid . . |
Accessions | G3V234 ENST00000428130.6 [Q8TC12-3] G3V510 H0YJ46 ENST00000554035.5 ENST00000557331.1 ENST00000557273.5 ENST00000381346.9 [Q8TC12-1] B3KQ19 A0A0S2Z575 ENST00000557726.1 G3V2G6 A0A0S2Z583 Q8TC12 ENST00000554731.1 ENST00000553384.5 [Q8TC12-2] G3V3K0 |