QSOX1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006457Biological processprotein folding
GO_0016242Biological processnegative regulation of macroautophagy
GO_0085029Biological processextracellular matrix assembly
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005615Cellular componentextracellular space
GO_0000139Cellular componentGolgi membrane
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0070062Cellular componentextracellular exosome
GO_1904724Cellular componenttertiary granule lumen
GO_0031093Cellular componentplatelet alpha granule lumen
GO_0005576Cellular componentextracellular region
GO_0005794Cellular componentGolgi apparatus
GO_0035580Cellular componentspecific granule lumen
GO_0045171Cellular componentintercellular bridge
GO_0071949Molecular functionFAD binding
GO_0003756Molecular functionprotein disulfide isomerase activity
GO_0016971Molecular functionflavin-dependent sulfhydryl oxidase activity

IV. Literature review

[source]
Gene nameQSOX1
Protein nameSulfhydryl oxidase 1 (hQSOX) (EC 1.8.3.2) (Quiescin Q6)
Quiescin sulfhydryl oxidase 1
SynonymsQSCN6
UNQ2520/PRO6013
DescriptionFUNCTION: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide . Plays a role in disulfide bond formation in a variety of extracellular proteins . In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration . .

AccessionsO00391
ENST00000443059.1
H0Y5Z8
ENST00000392029.6
ENST00000367600.5 [O00391-2]
ENST00000367602.8 [O00391-1]
A8MXT8