Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 5 studies | 33% ± 14% | |
classical monocyte | 4 studies | 22% ± 5% | |
conventional dendritic cell | 3 studies | 30% ± 8% | |
hematopoietic precursor cell | 3 studies | 20% ± 2% | |
non-classical monocyte | 3 studies | 24% ± 4% | |
ciliated cell | 3 studies | 25% ± 2% | |
effector CD4-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
macrophage | 3 studies | 21% ± 2% | |
dendritic cell | 3 studies | 33% ± 3% | |
regulatory T cell | 3 studies | 18% ± 1% | |
abnormal cell | 3 studies | 16% ± 1% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 18% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 1448.82 | 258 / 258 | 100% | 37.97 | 230 / 230 |
esophagus | 100% | 1833.86 | 1445 / 1445 | 100% | 27.59 | 183 / 183 |
liver | 100% | 1141.25 | 226 / 226 | 100% | 38.88 | 406 / 406 |
ovary | 100% | 780.88 | 180 / 180 | 100% | 41.08 | 430 / 430 |
pancreas | 100% | 756.52 | 328 / 328 | 100% | 42.80 | 178 / 178 |
prostate | 100% | 1535.18 | 245 / 245 | 100% | 77.71 | 502 / 502 |
skin | 100% | 1845.63 | 1809 / 1809 | 100% | 28.03 | 472 / 472 |
stomach | 100% | 912.56 | 359 / 359 | 100% | 35.75 | 286 / 286 |
thymus | 100% | 1402.23 | 653 / 653 | 100% | 54.47 | 605 / 605 |
uterus | 100% | 1037.65 | 170 / 170 | 100% | 54.69 | 459 / 459 |
kidney | 100% | 977.57 | 89 / 89 | 100% | 30.66 | 900 / 901 |
intestine | 100% | 1241.89 | 966 / 966 | 100% | 43.54 | 526 / 527 |
lung | 100% | 1110.30 | 576 / 578 | 100% | 43.78 | 1155 / 1155 |
bladder | 100% | 1151.76 | 21 / 21 | 100% | 57.23 | 502 / 504 |
breast | 100% | 1294.34 | 459 / 459 | 100% | 50.32 | 1113 / 1118 |
brain | 99% | 758.30 | 2625 / 2642 | 100% | 33.49 | 705 / 705 |
adipose | 100% | 1187.15 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 74.78 | 29 / 29 |
spleen | 100% | 1502.80 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 50.41 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 53.83 | 1 / 1 |
blood vessel | 100% | 1000.63 | 1333 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 678.94 | 796 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 25.71 | 79 / 80 |
heart | 97% | 564.80 | 833 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 95% | 917.19 | 883 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000184 | Biological process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
GO_1903259 | Biological process | exon-exon junction complex disassembly |
GO_0045727 | Biological process | positive regulation of translation |
GO_0005730 | Cellular component | nucleolus |
GO_0030054 | Cellular component | cell junction |
GO_0035145 | Cellular component | exon-exon junction complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0043022 | Molecular function | ribosome binding |
GO_0005515 | Molecular function | protein binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | PYM1 |
Protein name | WIBG protein PYM homolog 1, exon junction complex associated factor Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog) |
Synonyms | PYM WIBG |
Description | FUNCTION: Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA; the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC. . |
Accessions | ENST00000408946.7 [Q9BRP8-1] ENST00000454792.2 Q9BRP8 H0YJW5 Q96DC3 ENST00000398213.4 [Q9BRP8-2] ENST00000549939.1 F8VT68 |