Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 12 studies | 39% ± 16% | |
endothelial cell | 9 studies | 24% ± 9% | |
amacrine cell | 8 studies | 25% ± 9% | |
fibroblast | 8 studies | 19% ± 2% | |
oligodendrocyte precursor cell | 8 studies | 30% ± 15% | |
GABAergic neuron | 7 studies | 35% ± 19% | |
astrocyte | 7 studies | 31% ± 11% | |
glutamatergic neuron | 6 studies | 42% ± 22% | |
epithelial cell | 6 studies | 27% ± 6% | |
retina horizontal cell | 6 studies | 27% ± 7% | |
adipocyte | 6 studies | 22% ± 5% | |
retinal bipolar neuron | 5 studies | 31% ± 9% | |
interneuron | 5 studies | 38% ± 21% | |
microglial cell | 4 studies | 21% ± 3% | |
retinal cone cell | 4 studies | 26% ± 5% | |
type II pneumocyte | 4 studies | 20% ± 5% | |
ciliated cell | 3 studies | 22% ± 0% | |
lymphocyte | 3 studies | 20% ± 1% | |
Mueller cell | 3 studies | 19% ± 3% | |
glycinergic amacrine cell | 3 studies | 26% ± 4% | |
rod bipolar cell | 3 studies | 48% ± 6% | |
ependymal cell | 3 studies | 30% ± 17% | |
endothelial cell of lymphatic vessel | 3 studies | 17% ± 1% | |
macrophage | 3 studies | 19% ± 4% | |
pericyte | 3 studies | 19% ± 3% | |
transit amplifying cell | 3 studies | 24% ± 10% | |
smooth muscle cell | 3 studies | 21% ± 3% | |
granule cell | 3 studies | 23% ± 10% | |
neuron | 3 studies | 39% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1066.27 | 1445 / 1445 | 100% | 10.27 | 183 / 183 |
intestine | 100% | 1556.38 | 966 / 966 | 100% | 10.85 | 527 / 527 |
prostate | 100% | 1573.58 | 245 / 245 | 100% | 12.40 | 501 / 502 |
brain | 100% | 1361.36 | 2636 / 2642 | 100% | 10.48 | 705 / 705 |
ovary | 100% | 1309.09 | 180 / 180 | 100% | 8.77 | 429 / 430 |
lung | 100% | 1106.60 | 577 / 578 | 100% | 9.96 | 1154 / 1155 |
stomach | 100% | 1268.69 | 359 / 359 | 100% | 10.91 | 285 / 286 |
breast | 100% | 1208.30 | 459 / 459 | 100% | 11.76 | 1114 / 1118 |
uterus | 100% | 1516.38 | 170 / 170 | 100% | 10.68 | 457 / 459 |
bladder | 100% | 1507.33 | 21 / 21 | 99% | 8.72 | 501 / 504 |
thymus | 100% | 1432.43 | 653 / 653 | 99% | 9.88 | 601 / 605 |
adrenal gland | 100% | 1204.57 | 258 / 258 | 99% | 10.82 | 227 / 230 |
pancreas | 100% | 818.06 | 327 / 328 | 98% | 10.29 | 175 / 178 |
kidney | 100% | 1121.97 | 89 / 89 | 98% | 12.05 | 881 / 901 |
skin | 100% | 1413.02 | 1809 / 1809 | 95% | 8.62 | 449 / 472 |
liver | 100% | 662.04 | 226 / 226 | 94% | 5.09 | 382 / 406 |
adipose | 100% | 1248.39 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1414.06 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 8.74 | 29 / 29 |
spleen | 100% | 1698.29 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 10.72 | 45 / 45 |
heart | 99% | 680.21 | 851 / 861 | 0% | 0 | 0 / 0 |
muscle | 99% | 542.05 | 791 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 79% | 762.39 | 735 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 74% | 4.17 | 59 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001178 | Biological process | regulation of transcriptional start site selection at RNA polymerase II promoter |
GO_0032968 | Biological process | positive regulation of transcription elongation by RNA polymerase II |
GO_0006338 | Biological process | chromatin remodeling |
GO_0005634 | Cellular component | nucleus |
GO_0035064 | Molecular function | methylated histone binding |
GO_0120325 | Molecular function | NuRD complex binding |
GO_0005515 | Molecular function | protein binding |
GO_0042393 | Molecular function | histone binding |
GO_0003682 | Molecular function | chromatin binding |
Gene name | PWWP2A |
Protein name | PWWP domain containing 2A PWWP domain-containing protein 2A |
Synonyms | MST101 KIAA1935 |
Description | FUNCTION: Chromatin-binding protein that acts as an adapter between distinct nucleosome components (H3K36me3 or H2A.Z) and chromatin-modifying complexes, contributing to the regulation of the levels of histone acetylation at actively transcribed genes . Competes with CHD4 and MBD3 for interaction with MTA1 to form a NuRD subcomplex, preventing the formation of full NuRD complex (containing CHD4 and MBD3), leading to recruitment of HDACs to gene promoters resulting in turn in the deacetylation of nearby H3K27 and H2A.Z . Plays a role in facilitating transcriptional elongation and repression of spurious transcription initiation through regulation of histone acetylation (By similarity). Essential for proper mitosis progression . . |
Accessions | ENST00000523662.1 [Q96N64-3] ENST00000307063.9 [Q96N64-1] ENST00000521424.1 H0YC06 H0YB44 ENST00000456329.7 [Q96N64-2] ENST00000524050.5 Q96N64 |