PTRH2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_2000210Biological processpositive regulation of anoikis
GO_2000811Biological processnegative regulation of anoikis
GO_0010629Biological processnegative regulation of gene expression
GO_0005741Cellular componentmitochondrial outer membrane
GO_0005829Cellular componentcytosol
GO_0016020Cellular componentmembrane
GO_0005739Cellular componentmitochondrion
GO_0005515Molecular functionprotein binding
GO_0004045Molecular functionaminoacyl-tRNA hydrolase activity

IV. Literature review

[source]
Gene namePTRH2
Protein namePeptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription 1)
peptidyl-tRNA hydrolase (EC 3.1.1.29)
SynonymsCGI-147
BIT1
PTH2
DescriptionFUNCTION: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. .; FUNCTION: Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1. .

FUNCTION: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. .

AccessionsENST00000409433.2
Q9Y3E5
J3KQ48
ENST00000393038.3
ENST00000470557.2